Medication info
Cystat Tablets 40 mg (Simvastatin)

Cystat Tablets 40 mg (Simvastatin)

Prescription medicationTablet경구
Ingredient · strength
Simvastatin›40mg / 1 tablet
Manufacturer / importer
(주)보령
Appearance
Pale pink oval film-coated tablets
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 200300941 · Notified 2003.06.02 · Insurance code 641902730

Summary

Main use
Reduction of risk of cardiovascular diseases and improvement of hyperlipidemia
Who takes it
Adults · Children
Adult dose
Administer 20 mg once daily in the evening. For patients with mild to moderate hypercholesterolemia, starting with 10 mg may be appropriate. The recommended dosage is 5 to 40 mg once daily in the evening. Adjust the dosage based on initial LDL-cholesterol levels, therapeutic goals, and the patient's drug response before initiation. Recommended dosages vary for specific patient populations and when combined with other medications. For example, in cases of homozygous familial hypercholesterolemia
Child dose
For pediatric patients aged 10 to 17 with heterozygous familial hypercholesterolemia, administer 10 mg once daily in the evening. The recommended dosage range is 10 to 40 mg daily, with a maximum dosage of 40 mg daily.

Ingredients

Manufacturer
(주)보령

Efficacy & effects

Reduction of risk of cardiovascular diseases and improvement of hyperlipidemia

  • Coronary heart disease
  • diabetes
  • peripheral vascular disease
  • stroke
  • other cerebrovascular diseases
  • hypercholesterolemia
  • dyslipidemia
  • abnormal beta-lipoproteinemia
  • hypertriglyceridemia
  • heterozygous familial hypercholesterolemia
View approved original text

This medication has the efficacy of reducing the risk of cardiovascular diseases. It reduces the risk of coronary events, myocardial infarction, and stroke in adult patients with a history of coronary heart disease, diabetes, peripheral vascular disease, or stroke. It also helps to lower the risk of complications after vascular procedures. It is used to treat hyperlipidemia and improves various dyslipidemia conditions, including primary hypercholesterolemia, familial and non-familial dyslipidemia, and hypertriglyceridemia. It is used effectively to lower cholesterol levels in young children with familial hypercholesterolemia in conjunction with dietary measures. This medication is used comprehensively to promote cardiovascular health and reduce risks.

How to take

Adult dose

Administer 20 mg once daily in the evening. For patients with mild to moderate hypercholesterolemia, starting with 10 mg may be appropriate. The recommended dosage is 5 to 40 mg once daily in the evening. Adjust the dosage based on initial LDL-cholesterol levels, therapeutic goals, and the patient's drug response before initiation. Recommended dosages vary for specific patient populations and when combined with other medications. For example, in cases of homozygous familial hypercholesterolemia

Child dose

For pediatric patients aged 10 to 17 with heterozygous familial hypercholesterolemia, administer 10 mg once daily in the evening. The recommended dosage range is 10 to 40 mg daily, with a maximum dosage of 40 mg daily.

Precautions

This medication primarily acts in the liver to lower blood cholesterol levels. However, it may affect muscles and cause symptoms such as muscle pain or weakness. The risk of muscle damage may be higher, especially when taking high doses, so caution is needed. If symptoms like muscle pain, tenderness, or weakness occur during treatment, it is necessary to consult a doctor immediately. Patients with liver dysfunction or active liver disease should not take this medication. Women who are pregnant, potentially pregnant, or breastfeeding should not take this medication. Also, taking this medication with certain antifungal agents, antibiotics, immunosuppressants, or blood pressure medications can increase the risk of muscle damage; therefore, be sure to inform the doctor of all medications currently being taken. This medication can affect liver function, so regular liver function tests are advisable. Elderly patients or those with impaired renal function are at a higher risk of muscle damage while taking this medication and should be monitored closely. While taking this medication, it is advisable to avoid certain foods such as grapefruit juice, and it is safe to limit alcohol consumption during treatment. This medication is restricted for use in children, specifically in patients with certain hypercholesterolemia conditions, and should not be administered to children under 10 years of age. If any abnormal symptoms appear during treatment, immediate consultation with medical staff is essential, and care should be taken not to discontinue the medication on your own.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory distress with cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

  • Abdominal pain
  • fatigue
  • constipation
  • diarrhea
  • dyspepsia
  • bloating
  • nausea
  • headache
  • upper respiratory infection
  • atrial fibrillation
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  • gastritis
  • diabetes
  • myalgia
  • insomnia
  • dizziness
  • bronchitis
  • pharyngitis
  • eczema
  • urinary tract infection
  • alopecia
  • pruritus
  • skin/mucous membrane dryness
  • hair/nail changes
  • drug eruption resembling lichen planus
  • gynecomastia
  • decreased libido
  • sexual dysfunction
  • progression of cataracts
  • ocular muscle paralysis
  • anemia
  • thyroid dysfunction
  • serum creatine kinase

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air and moisture, so it should be stored in a sealed container. The storage temperature should be between 1 and 30 degrees Celsius, and it is advisable to avoid very hot or very cold places.

Appearance and packaging

Appearance

Pale pink oval film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.