Conil Tablet 8 mg (Benidipine Hydrochloride)

Adult dose

Hypertension: Administer 2 ～ 4 mg of benidipine hydrochloride orally once daily after breakfast. If the effect is insufficient, the dose may be increased to 8 mg once daily. However, for severe hypertension, administer 4 ～ 8 mg orally once daily after breakfast. Angina pectoris: Administer 4 mg of this drug per dose orally 2 times daily after breakfast and dinner. Adjust the dose as appropriate according to symptoms.

This medication should not be used in patients with cardiogenic shock, women who are pregnant or may become pregnant, breastfeeding mothers, and children. This medication contains lactose, so individuals with lactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption syndrome should avoid taking it. Caution should be exercised when using this medication in patients with excessively low blood pressure, severe liver dysfunction, and the elderly. In particular, starting with a low dose in the elderly and closely monitoring their condition is required. Periodic liver function tests may be necessary due to the potential for liver dysfunction or jaundice symptoms, and if abnormalities are found, discontinuation of the medication is required. Since it may affect kidney function, regular kidney-related tests are recommended. Blood tests may show leukopenia or thrombocytopenia, so close observation of blood counts is needed. Cardiovascular symptoms like irregular heartbeats, facial flushing, heat sensation, and lowered blood pressure may occur, thus immediate consultation with medical personnel is advised if these symptoms arise. CNS side effects such as headaches, dizziness, and drowsiness may occur, so caution is needed when driving or operating dangerous machinery. Gastrointestinal symptoms such as constipation, nausea, and abdominal discomfort may occur, and severe cases should be reported to medical personnel. In case of hypersensitivity reactions like rash, itching, or photosensitivity reactions, immediately discontinue use and consult medical personnel. Symptoms such as facial or limb swelling, elevated muscle enzymes, fatigue, tinnitus, and reddening and heat sensation in the hands may occur, requiring observation of symptoms. Abrupt discontinuation of this medication can worsen symptoms; therefore, dosage should be gradually reduced according to the physician's instructions, and it should not be stopped arbitrarily. Co-administration with other antihypertensive agents may enhance effects, so caution should be exercised when used together. Using certain medications or grapefruit juice may lead to excessive blood pressure reduction, so consultation with medical personnel is essential. Pregnant or breastfeeding women should avoid this medication. If it must be used, breastfeeding should be ceased. In children, the safety of use has not been established, so its use is not recommended. In case of overdose, severe blood pressure reduction may occur, requiring immediate treatment at a medical facility, and this medication is not removed by dialysis. This medication should be used strictly as instructed by a physician, and if tablets are split for dosing, they should be taken as soon as possible after splitting.

• Liver dysfunction
• jaundice
• elevated BUN
• elevated creatinine
• leukopenia
• increased eosinophils
• thrombocytopenia
• palpitations
• facial flushing
• heat sensation

This medication should be stored in a tightly sealed container to prevent air or moisture intrusion. It is important to maintain storage temperatures between 1 to 30 degrees Celsius.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle, 200 tablets/bottle