Roxitide Tablets (Roxithromycin)

Adult dose

Adults: Administer 150㎎ (potency) of roxithromycin orally twice daily, in the morning and evening before meals. For pneumonia, administer 300mg (potency) once daily before breakfast. Adjust the dose appropriately according to age and symptoms.

Child dose

Children: In clinical trials, the average dose used was 6mg (potency) per kg of body weight per day. This medicine is administered orally in 2 divided doses of 5～8mg (potency) per kg of body weight per day. The dose according to body weight is as follows. Children weighing 6～11Kg: Take 25mg (potency) per dose twice daily before meals (pediatric tablets and granules only), or 2.5mL per dose twice daily before meals (suspension only). Children weighing 12～23Kg: Take 50mg (potency) per dose twice daily before meals (pediatric tablets and granules only), or 5mL per dose twice daily before meals (suspension only). Children weighing 24～40Kg: Take 100mg (potency) per dose twice daily before meals (pediatric tablets and granules only), or 10mL per dose twice daily before meals (suspension only).

This medication can cause serious skin adverse reactions, such as severe blistering skin reactions, so if symptoms of blistering on the skin or mucosal damage occur, discontinue use immediately. Patients with allergies to this drug or similar classes of antibiotics, or those taking certain medications, should not take this drug. It should be administered cautiously to patients with impaired liver function or elderly patients, and care should be taken regarding drug interactions or side effects when used with other antibiotics. Possible cardiac side effects require caution in patients with heart disease or those taking certain antiarrhythmic medications. This drug may exacerbate myasthenia gravis, requiring patients with this condition to consult a physician before use. Various side effects, including allergic reactions, liver function abnormalities, gastrointestinal disturbances, respiratory problems, and neurological issues, may occur, so any unusual symptoms should be reported to medical professionals immediately. Particularly if there is severe diarrhea or abdominal pain, the possibility of Clostridium difficile colitis should be considered, and hospitalization should be pursued immediately stopping the medication. This drug may cause drug interactions by interfering with the metabolism of other medications in the liver, so patients must inform healthcare providers of any other medications they are taking. Pregnant women or those who may become pregnant should consult a physician before using this medication, as it may affect the fetus. Breastfeeding may need to be discontinued, as this drug can be transmitted through breast milk. Symptoms such as dizziness or blurred vision may occur, necessitating caution when operating machinery or driving. Finally, this drug should be stored out of reach of children and should not be transferred to other containers.

Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, shock, anaphylactic shock, fever, rash, allergic skin reactions, angioedema, eosinophilia, agranulocytosis, leukopenia, thrombocytopenia, cholestatic acute hepatitis, hepatocellular acute hepatitis, jaundice, elevated AST, elevated ALT, elevated ALP, increased serum bilirubin, anorexia, nausea, vomiting, upper abdominal discomfort, dyspepsia, stomach pain, abdominal pain, abdominal distension, diarrhea, pseudomembranous colitis, loose stools, hemorrhagic colitis, bloody stools, pancreatitis, bronchospasm, cough, dyspnea, abnormal chest X-ray, interstitial pneumonia, drowsiness, headache, dizziness, tongue numbness, paralysis, taste disorders, ageusia, olfactory abnormalities, anosmia, erythema multiforme, purpura, secondary infections due to excessive growth of non-susceptible pathogens, transient hearing loss, hearing impairment, visual disturbances, blurred vision, conjunctival injection, generalized malaise, weakness, palpitations, QT prolongation, ventricular tachycardia, arthralgia, epistaxis, menstrual irregularities, inflammation of the oral and vaginal mucosa, hallucinations, confusion

This drug should be stored in a tightly sealed container to protect it from air and moisture. It is recommended to maintain a room temperature between 1°C and 30°C, and the medication remains effective for 36 months from the manufacturing date.

Appearance

White round tablet

Package unit

30 tablets/bottle, 100 tablets/bottle