Glimapin Tablet (Gliclazide)

Adult dose

Adjusted individually for each patient. Swallow without chewing with more than 1/2 cup of water. This medication is taken orally once daily. It should be taken before breakfast or right before the first meal. The initial dose for monotherapy starts at 1 mg once daily and can be increased by 1 mg at intervals of 1-2 weeks. Generally, there is little additional benefit when doses over 4 mg are administered; however, if necessary, doses may be raised to 6-8 mg.

This medication should not be used in patients with insulin-dependent diabetes or those with diabetic ketoacidosis or in a comatose state. Additionally, it is advisable to avoid administering this medication to patients who are allergic to this drug or sulfonylurea drugs, or those with severe liver or kidney dysfunction. Pregnant or possibly pregnant women and nursing mothers should not use this medication. Insulin therapy is recommended for patients with severe infections, before and after surgery, or those with severe trauma. Patients with gastrointestinal disorders such as diarrhea or vomiting should be cautious as these conditions can impede food absorption, increasing the risk of hypoglycemia. During the first week of administration of this medication, the risk of hypoglycemia is high, hence blood glucose levels should be closely monitored. Particularly, elderly patients, those with poor nutritional status, those who eat irregularly, those who frequently consume alcohol, and those with impaired liver or kidney function should be even more cautious. Also, when taking other medications, changes in blood sugar levels may occur, so it is essential to inform the physician or pharmacist of all current medications. This medication can cause hypoglycemia, with symptoms including headache, severe hunger, nausea, fatigue, anxiety, confusion, dizziness, drowsiness, and decreased consciousness. In case of hypoglycemia, immediate consumption of sugar-containing food is required, and if symptoms are severe or recurrent, the patient should consult a physician. During the use of this medication, symptoms such as blurred vision, indigestion, abnormal liver function, blood abnormalities, or allergic reactions may appear. If any abnormal symptoms occur, medical personnel should be notified immediately. To control blood sugar, regular intake of this medication along with dietary therapy, exercise therapy, and weight management is crucial. During the use of this medication, being informed about symptoms and risks of hypoglycemia, along with treatment methods, is important, and patients should be prepared to consume sufficient sugar. In addition, insulin therapy may need to be switched to when conditions such as stress, surgery, or infection make blood sugar control difficult. Severe hypoglycemia can occur in case of overdose, so in case of overdose, immediate emergency treatment must be obtained, and blood sugar levels should be closely monitored for at least 24 to 48 hours thereafter. This medication has not been established for safety and efficacy in children, and elderly patients may require dosage adjustment due to decreased kidney function. Finally, this medication should be kept out of the reach of children and stored in its original container.

Serious side effects

Hives, severe swelling (edema), chest tightness, shortness of breath, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, jaundice (yellowing of skin or eyes), profound lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, significant decrease in urine output, severe swelling throughout the body with elevated blood pressure, thrombocytopenia, leukopenia.

Mild side effects

• Headache
• severe hunger
• nausea
• vomiting
• fatigue
• sleep disturbances
• anxiety
• aggression
• decreased concentration
• decreased agility or activity

Store this medication in a tightly closed container to protect it from air and moisture. The storage temperature should be maintained at room temperature between 1 degree and 30 degrees Celsius. This will help preserve the effectiveness and safety of the medication for a long time.

Appearance

Green rectangular tablet

Package unit

30 tablets/box [(10 tablets/PTPX3)], 30 tablets/bottle, 100 tablets/bottle, 500 tablets/bottle