Medication info
Glimepiride 2 mg Tablet

Glimepiride 2 mg Tablet

Prescription medicationTablet경구
Ingredient · strength
Glimepiride›2mg / 1 tablet
Manufacturer / importer
동화약품(주)
Appearance
Green oblong tablet
Packaging
30 tablets/bottle
Approval status
Active

MFDS item code 200300530 · Notified 2003.12.06 · Insurance code 642700040

Summary

Main use
Improvement of blood glucose control in type 2 diabetes
Who takes it
Adults
Adult dose
This medication is taken orally once a day. It should be taken before breakfast or immediately before the first meal, and swallowed whole with more than half a cup of water. For monotherapy, start with a dose of 1 mg of glimepiride once daily and increase by 1 mg at intervals of 1 to 2 weeks. Generally, there is little additional effect when doses beyond 4 mg are used, but in some cases, doses of 6 mg or 8 mg can achieve better metabolic control.

Ingredients

Manufacturer
동화약품(주)

Efficacy & effects

Improvement of blood glucose control in type 2 diabetes

View approved original text

This medicine is used in conjunction with diet and exercise to help control blood sugar in patients with type 2 diabetes. It can be used as monotherapy, and sometimes in combination with oral hypoglycemic agents or insulin to enhance its effectiveness. In particular, this medication may be taken together with metformin when sufficient blood glucose control is not achieved with sulfonylureas or metformin monotherapy. Such combination therapy aids in improving blood glucose control. Overall, this medication is effectively used in managing blood sugar levels in type 2 diabetes patients.

How to take

Adult dose

This medication is taken orally once a day. It should be taken before breakfast or immediately before the first meal, and swallowed whole with more than half a cup of water. For monotherapy, start with a dose of 1 mg of glimepiride once daily and increase by 1 mg at intervals of 1 to 2 weeks. Generally, there is little additional effect when doses beyond 4 mg are used, but in some cases, doses of 6 mg or 8 mg can achieve better metabolic control.

Precautions

This medication should not be used in patients with insulin-dependent diabetes, diabetic ketoacidosis, or those who are in a coma. Additionally, patients who have allergies to this medication, sulfonylureas, or sulfonamides should not be administered this drug. Due to no experience using this medicine in patients with severe liver or kidney dysfunction, transitioning to insulin therapy is recommended. Women who are pregnant or may become pregnant, as well as nursing mothers, should not take this medication. Patients with severe infections, or those undergoing surgery or severe trauma may also need insulin treatment and should exercise caution. Patients with gastrointestinal disorders may absorb food poorly, increasing the risk of hypoglycemia. This medication contains lactose, and should not be given to patients with lactose intolerance or certain genetic issues. During the initial treatment period, there is a high risk of hypoglycemia, so blood sugar levels should be frequently monitored. Particularly elderly patients or those with poor nutritional status, irregular eating patterns, excessive exercise, or changes in diet should be particularly cautious. Patients who frequently consume alcohol or have weakened kidney or liver function may also have an increased risk of hypoglycemia. Caution should also be taken if there are other endocrine disorders or if multiple medications are taken, and dosage adjustments should be discussed with a doctor if these situations arise. This medication can cause hypoglycemia, with symptoms including headaches, severe hunger, nausea, fatigue, anxiety, confusion, dizziness, drowsiness, and decreased consciousness. Additionally, symptoms like sweating and palpitations may accompany these; if symptoms arise, immediate intake of sugar is necessary. While visual disturbances, gastrointestinal disorders, liver function abnormalities, blood dyscrasias, and allergic reactions may occur rarely, any unusual symptoms should be reported to a physician. In cases of severe hypoglycemia or serious allergic reactions, medication should be stopped immediately and medical assistance sought. This medication should be taken consistently to control blood sugar, with diet and exercise also incorporated into the routine. If hypoglycemic symptoms occur, sugar-containing foods should be consumed immediately, as artificial sweeteners are ineffective. During times of stress, surgery, or infections that make controlling blood sugar difficult, temporary transition to insulin therapy may be necessary. When starting treatment or changing doses, blood sugar levels should be monitored closely, and caution is advised when driving or operating machinery. This medication can interact with other drugs, so if there are medications being taken concurrently, it is essential to inform the physician or pharmacist. Particularly, certain antibiotics, antifungals, anti-inflammatories, beta-blockers, and alcohol may affect the efficacy of this medication. Pregnant or nursing women should avoid this medication due to potential risks to the fetus and neonate, and if necessary, transition to insulin therapy should be considered. Safety and efficacy in children under 18 years of age have not been established. Elderly patients should be careful as kidney function may decline, and dosage adjustments should be considered. Overdosage may lead to severe hypoglycemia, necessitating immediate medical attention for appropriate treatment. This medication should be kept out of reach of children and stored in its original container to maintain quality.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), difficulty breathing, chest tightness, severe allergic reactions, serious skin reactions, yellowing of the skin or eyes (jaundice), severe fatigue throughout the body, liver abnormalities, sudden and severe headaches, seizures, confusion, visual disturbances, paralysis, serious neurological symptoms, markedly reduced urine output, severe edema and increased blood pressure, severe swelling or urination abnormalities, thrombocytopenia.

Mild side effects

  • Headaches
  • severe hunger
  • nausea
  • vomiting
  • fatigue
  • sleep disturbances
  • anxiety
  • aggression
  • decreased concentration
  • decreased agility or energy
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  • depression
  • confusion
  • speech disorders
  • aphasia
  • visual disturbances
  • tremors
  • partial paralysis
  • sensory disturbances
  • dizziness
  • weakness
  • loss of self-control
  • temporary mental confusion
  • seizures
  • drowsiness
  • loss of consciousness
  • shallow breathing
  • bradycardia
  • sweating
  • cold and clammy skin
  • tachycardia
  • hypertension
  • palpitations
  • angina
  • arrhythmias
  • visual problems.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to prevent air from entering and kept at room temperature between 1 degree and 30 degrees Celsius. Storing it this way will maintain the medication's effectiveness and prevent degradation.

Appearance and packaging

Appearance

Green oblong tablet

Package unit

30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.