Diabex Tablets 1000 mg (Metformin Hydrochloride)

Adult dose

The dosing should be determined based on the drug's efficacy and tolerance for each individual, ensuring not to exceed the recommended maximum daily dose. Start with a low dose, administering 500 mg 2-3 times daily with meals. The dosage may increase gradually by 500 mg weekly, and when dosing up to 2000 mg, it is generally administered twice a day in the morning and evening. If over 2000 mg is necessary,

Child dose

Can be used for children over 10 years old or adolescents in growth stages. Generally, the starting dose is 500 mg once daily during or after meals. Blood sugar levels should be tested after one week to adjust the dosage.

This medication can cause severe lactic acidosis or hypoglycemia, so if these symptoms occur, medical attention should be sought immediately. Patients with moderate to severe renal impairment, dehydration, severe infections, cardiovascular collapse, acute myocardial infarction, sepsis, or other acute conditions should not use this medication. Patients with acute or unstable heart failure should not be administered this medication, and it should be discontinued for a certain period before and after tests using iodine-containing radiocontrast agents. This medication is not to be administered to patients allergic to this drug or biguanides, those with type 1 diabetes, lactic acidosis, or diabetic ketoacidosis. In patients with severe infections, severe traumatic systemic disorders, those scheduled for surgery, malnutrition, liver function impairment, lung function impairment, and excessive alcohol consumption, the use of this medication should be carefully considered. This medication can lead to a rare side effect known as lactic acidosis, so if symptoms such as malaise, muscle pain, difficulty breathing, or abdominal pain occur, immediate consultation with a doctor is necessary. Gastrointestinal side effects may include diarrhea, nausea, vomiting, and abdominal bloating, which are usually temporary, but if severe, treatment adjustment may be required. Regular monitoring of renal function, blood sugar, and vitamin B12 levels is necessary while taking this medication to check for abnormalities. Alcohol consumption can affect lactic acid metabolism and increase the risk of lactic acidosis, so excessive drinking should be avoided during treatment. This medication may interact with other hypoglycemic agents or certain medications, so it is essential to inform the doctor or pharmacist of any ongoing medications. During pregnancy, the use of this medication should be decided while closely observing the condition of the fetus and mother, and its use is not recommended during breastfeeding. Elderly patients may have impaired renal function, hence appropriate dosing adjustment and regular renal function testing are necessary. In the case of overdose, the drug can be removed via dialysis, so immediate medical attention should be sought in case of exceeding the dosage. This medication does not cause weight gain, making it advantageous for diabetic patients who need to manage their weight, and it is important to maintain dietary therapy and regular exercise during treatment. Keep out of reach of children, and ensure it is not transferred to another container.

Serious side effects

Hives, severe swelling (edema), lactic acidosis, severe allergic reactions, liver abnormalities (potential for jaundice), severe swelling or urinary abnormalities (including renal function decline), difficulty breathing (related to lactic acidosis and hypoxia), severe skin adverse reactions (including erythema, rash, hives), serious neurological symptoms (seizures, confusion of consciousness, etc.), severe cases of hypoglycemia

Mild side effects

Gastrointestinal symptoms (diarrhea, nausea, vomiting, abdominal bloating, loss of appetite, indigestion, constipation, abdominal pain), sensory symptoms (unpleasant metallic taste), skin symptoms (erythema, itching, rash), blood abnormalities (anemia, leukopenia, thrombocytopenia, vitamin B12 deficiency), liver function abnormalities, hypoglycemia symptoms (rarely severe delayed hypoglycemia)

This medication should be stored in a tightly closed container to protect it from air and moisture. Additionally, it is advisable to store it at room temperature between 1 degree to 30 degrees Celsius.

Appearance

White rectangular film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle