Bendipine Tablets (Benidipine Hydrochloride)

Adult dose

○ Adults Hypertension: Administer 2 ～ 4 mg of benidipine hydrochloride orally once daily after breakfast. If the effect is insufficient, the dose may be increased to up to 8 mg once daily. However, for severe hypertension, administer 4 ～ 8 mg orally once daily after breakfast. Angina: Administer 4 mg of this drug orally twice daily after breakfast and dinner. Adjust the dose appropriately according to symptoms.

This drug should not be used in patients with cardiogenic shock. It is advisable not to administer it to pregnant women or women who may become pregnant, as well as to nursing women. Its safety has not been established in children, so it should not be used. This drug contains lactose, therefore it should not be administered to patients with lactose intolerance or certain genetic disorders. Care should be taken when administering to patients with excessively low blood pressure, severe liver dysfunction, and the elderly. Liver function should be carefully monitored as liver dysfunction or jaundice may occur. It may affect kidney function, so kidney-related tests should be regularly performed. There may be abnormal findings such as leukopenia or thrombocytopenia in blood tests, so caution is advised. Cardiovascular symptoms such as palpitations, facial flushing, and hypotension may occur. Additionally, neurological symptoms such as dizziness, headache, and drowsiness may appear, so care should be taken when driving or performing hazardous tasks. Gastrointestinal symptoms such as constipation, nausea, and abdominal discomfort may occur. If hypersensitivity reactions such as rash, itching, or photosensitivity occur, administration should be discontinued immediately. Various other symptoms such as facial or limb swelling, fatigue, and tinnitus may occur; if any abnormal symptoms arise, they should be reported. Discontinuing this medication suddenly may worsen symptoms; therefore, it should be tapered off according to a physician's directions. Excessive blood pressure lowering or transient loss of consciousness may occur, so appropriate measures should be taken if these symptoms appear. When used with other antihypertensive agents, the blood pressure-lowering effect may be enhanced, so caution is necessary. Co-administration with certain medications or grapefruit juice may exacerbate blood pressure lowering; therefore, these should not be taken together. Pregnant or nursing women are advised to avoid this medication, but if necessary, it is recommended to discontinue breastfeeding. In elderly patients, treatment should start at a low dose, carefully monitoring their condition. In cases of overdose, blood pressure may drop excessively, and immediate medical attention should be sought. This medication should be used according to the physician's prescription and guidance, and if the tablets are divided for use, they should be taken promptly. Patients undergoing chronic peritoneal dialysis should be vigilant as symptoms similar to peritonitis may occur with this medication.

• Liver dysfunction
• jaundice
• elevated BUN
• elevated creatinine
• leukopenia
• increased eosinophils
• thrombocytopenia
• palpitations
• facial flushing
• heat sensations

This medication should be stored in a tightly sealed container to prevent air exposure, and it is recommended to store it at room temperature between 1 and 30 degrees Celsius. Proper storage will maintain the medication's efficacy and prevent degradation.

Appearance

Yellow, round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle, 300 tablets/bottle