Budenotide Inhalation Solution (Unrefined Budesonide)

Adult dosage

This medication should be administered using an appropriate nebulizer. The dose delivered to the patient is approximately 40~60% of the labeled dose, depending on the nebulizer used. Nebulization time and dose vary according to the flow rate, nebulizer chamber, and fill volume. A fill volume of 2~4ml is suitable for most nebulizers. Bronchial asthma — At the start of inhalation therapy, during treatment of severe asthma, or when reducing or discontinuing oral corticosteroids: Adults: Administer 1~2mg (2 bottles~4 bottles) twice daily Bronchial asthma — Maintenance dose: Adults: Administer 0.5~1mg (1 bottle~2 bottles) twice daily

Children's dosage

Bronchial asthma — At the start of inhalation therapy, during treatment of severe asthma, or when reducing or discontinuing oral corticosteroids: Children: Administer 0.5~1mg (1 bottle~2 bottles) twice daily Bronchial asthma — Maintenance dose: Children: Administer 0.25~0.5mg (1/2 bottle~1 bottle) twice daily Acute laryngotracheobronchitis — Infants and young children: Administer 2mg once daily.

This drug is an inhaler containing budesonide, used for treating asthma and chronic pulmonary diseases. Firstly, those who are allergic to this medication or have experienced side effects should not use it. Patients with pulmonary tuberculosis or fungal, viral infections should exercise special caution when using this medication. Patients reliant on oral steroids need to switch to this drug cautiously, starting with concurrent oral steroids while gradually reducing the dosage. Using this medication may cause sore throat, inflammation in the mouth, dryness, cough, hoarseness, etc. It is particularly important to rinse the mouth thoroughly with water after inhalation to prevent oral candidiasis (fungal infection). Rarely, side effects such as headaches, taste abnormalities, skin rashes, bronchospasms, anxiety, and depression may occur. To prevent bronchospasms, it is advisable to use a bronchodilator 5-10 minutes before inhaling this medication. Since this drug may cause facial irritation, it is recommended to wash the face after use. This medication is not intended for rapid relief of acute asthma attacks, so it should not be used alone during severe symptoms. When switching from oral steroids to this drug, recovery of adrenal function takes time, so it should be done under the guidance of a physician. In cases of asthma exacerbation due to bacterial infections, antibiotic therapy and dosage adjustments may be necessary. When discontinuing this medication, consulting a doctor or pharmacist is essential, and it is necessary to check for the history of varicella or measles and vaccination status to reduce infection risks. During pregnancy, this drug can be used for asthma management and is reported to pose no significant risk to the fetus. While breastfeeding, the inhalation amount of this drug is low, and it is expected to have minimal effects on the infant through breast milk. When used by children, it should be administered in minimal amounts to avoid impacting growth, with regular checks on their growth status. Overdosage may not commonly cause serious issues, but prolonged overdosage can lead to side effects such as adrenal suppression. After inhalation, the mouth and face should be thoroughly washed to reduce the occurrence of candidiasis; if sediment occurs during storage, it should be discarded if it does not mix well even after shaking. It should be used within 3 months after opening, and the aerosol solution is only for inhalation and should not be swallowed or injected.

• Sore throat
• oral and glossitis
• dry mouth
• cough
• oral candidiasis
• hoarseness
• laryngitis
• headache
• cranial discomfort
• taste disturbances

This drug should be stored in a tightly closed container to prevent moisture or air from entering, and it is safe to keep it at room temperature between 1°C and 30°C. Storing it this way will help maintain the drug's efficacy and prevent degradation.

Appearance

A uniform white to grayish-white suspension for inhalation filled in a single-use plastic bottle.

Package unit

2 milliliters/bottle