Crestor 10 mg (Rosuvastatin Calcium)

Adult dose

Administer 5 mg once daily at any time of day, regardless of meals. If further reduction in LDL cholesterol is necessary, the maintenance dose can be adjusted, with 10 mg once daily being the typical adjustment for most patients. The maintenance dose should be adjusted periodically over 4 weeks or more based on LDL cholesterol levels, treatment goals, and patient response, with a maximum daily dose of 20 mg.

Child dose

In pediatric patients with heterozygous familial hypercholesterolemia (aged 10 to 17 years), administer 5 mg to 20 mg once daily. The dosage should be adjusted based on the individual patient's treatment goals over intervals of 4 weeks or more.

This drug should not be used in certain patients. For example, it should not be administered to individuals with an allergy to this drug, patients with liver disease, myopathy, severe kidney impairment, or women who are pregnant or breastfeeding. Before taking this medication, it is essential to periodically examine liver function and muscle condition, particularly for patients with a history of liver disease or significant alcohol intake. If symptoms such as muscle pain or weakness occur, inform a physician immediately. Furthermore, this drug may interact with other medications, so it is crucial to inform healthcare providers of any medications being taken. Certain medications may elevate the blood concentration of this drug, increasing the risk of muscle damage. Women who may become pregnant should use appropriate contraception while taking this medication and must discontinue usage immediately if they become pregnant. It is also advised that breastfeeding women avoid taking this medication. In case of an overdose, there is no specific antidote, and treatment should be symptomatic, with monitoring of liver function and muscle enzyme levels. This drug may cause side effects such as dizziness, so caution is advised when driving or operating machinery. Lastly, this drug may show higher concentrations in Asians, and dosage adjustments may be necessary.

Serious side effects

Urticaria, angioedema, severe edema, chest tightness, difficulty breathing, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), jaundice, hepatitis, acute renal failure, oliguria, thrombocytopenia, increased serum creatinine, rhabdomyolysis, severe muscle weakness, ocular myasthenia, fatal and non-fatal liver failure, severe allergic reactions, severe skin reactions, respiratory problems

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• muscle pain
• weakness
• cough

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is important to maintain storage temperatures between 1 and 30 degrees Celsius. Storing it this way helps ensure the drug's effectiveness is preserved.

Appearance

Pink round film-coated tablet

Package unit

30 tablets/bottle, 30 tablets (15 tablets/PTP×2)