Medication info

Hemozol B Zero Solution

Prescription medication주사
Ingredient · strength
Lactic Acid›5.4gMagnesium Chloride Hexahydrate›0.103gCalcium Chloride Hydrate›0.257gSodium Lactate›0.336gSodium Bicarbonate›2.69gSodium Chloride›6.14g
Manufacturer / importer
밴티브코리아주식회사
Appearance
Colorless and transparent liquid preparation contained in a transparent Polyolefin bag.
Packaging
5000ml/bag
Approval status
Active

MFDS item code 200209451 · Notified 2002.09.10 · Insurance code 646601671

Summary

Main use
Effective for acute renal failure patients (such as hyperkalemia) as a fluid replacement and dialysis solution.
Who receives it
Adults · Children
Adult administration
Generally, during blood filtration and dialysis, the flow rate for fluid replacement is 500 - 3000 mL/h. During continuous dialysis, the dialysis flow rate is 500 - 2500 mL/h. The usual flow rate for adults is approximately 2000 - 2500 mL/h, which corresponds to a daily fluid replacement volume of about 48 - 60 L. For elderly patients, the administration method follows that of adults, but the infusion rate is determined based on the patient's condition.
Child administration
During blood filtration and dialysis, the flow rate for fluid replacement is 1000 - 2000 mL/h/1.73m2. During continuous dialysis, the dialysis flow rate is 1000 - 2000 mL/h/1.73m2. In particular, during continual

Ingredients

Importer
밴티브코리아주식회사

Efficacy & effects

Effective for acute renal failure patients (such as hyperkalemia) as a fluid replacement and dialysis solution.

  • Acute renal failure
  • hyperkalemia
View approved original text

This medicine is primarily used in the treatment of acute renal failure patients. It is used as a fluid replacement during continuous blood filtration or dialysis and is utilized as a dialysis solution during continuous blood dialysis. It is particularly effective for patients with hyperkalemia, meaning elevated potassium levels in the blood. It helps regulate the body's electrolyte balance and supports kidney function, thereby improving symptoms. Therefore, it is used in the treatment of acute renal failure patients.

How it is given

Adult administration

Generally, during blood filtration and dialysis, the flow rate for fluid replacement is 500 - 3000 mL/h. During continuous dialysis, the dialysis flow rate is 500 - 2500 mL/h. The usual flow rate for adults is approximately 2000 - 2500 mL/h, which corresponds to a daily fluid replacement volume of about 48 - 60 L. For elderly patients, the administration method follows that of adults, but the infusion rate is determined based on the patient's condition.

Child administration

During blood filtration and dialysis, the flow rate for fluid replacement is 1000 - 2000 mL/h/1.73m2. During continuous dialysis, the dialysis flow rate is 1000 - 2000 mL/h/1.73m2. In particular, during continual

Precautions

This medication should not be used in patients with allergies to the active ingredients or excipients. In particular, solutions containing lactic acid should not be administered to patients with severe metabolic acidosis or reduced lactic acid metabolism capacity, as it may worsen the acidosis and lead to cardiac dysfunction. This medication should be used cautiously in patients with severe liver dysfunction, sepsis, or heart failure, and caution is required when used as a fluid replacement. Since this medication does not contain potassium, patients with hypokalemia should be especially cautious, as excessive use may lead to serious side effects such as heart failure or electrolyte imbalance. Before and during treatment, careful observation of the patient's electrolyte status and acid-base balance is crucial, and appropriate measures should be taken if necessary. Furthermore, this medication does not contain glucose, which may lead to hypoglycemia; therefore, blood glucose levels should be regularly checked. As it contains lactate and bicarbonate, if metabolic alkalosis occurs or is exacerbated, the rate of administration may need to be reduced or stopped. When used with other medications, caution regarding interactions is required, particularly with calcium preparations or vitamin D preparations due to the risk of hypercalcemia. During pregnancy or breastfeeding, it should only be used if the benefits outweigh the risks. In case of overdose, immediate discontinuation of administration is necessary, and monitoring and appropriate treatment for electrolyte and acid-base imbalances are required. This medication can be warmed to 37 degrees Celsius before use; however, it should not be heated in the microwave or directly in water. The solution must be checked to be transparent and the container undamaged. The solution should be handled aseptically, and any unused mixed solution should be discarded immediately after use. When storing, it should not be kept at temperatures below 4 degrees Celsius and should not be stored for more than 24 hours after mixing. There are no reports of it affecting driving or operating machinery.

Side effects and when to seek care immediately

Mild side effects

  • Electrolyte imbalance
  • hypophosphatemia
  • hypokalemia
  • acid-base balance disorders
  • fluid imbalance
  • hypotension
  • nausea
  • vomiting
  • muscle cramps

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container and should not be stored at low temperatures below 4 degrees Celsius. Proper storage conditions help maintain the efficacy and safety of the medication.

Appearance and packaging

Appearance

Colorless and transparent liquid preparation contained in a transparent Polyolefin bag.

Package unit

5000ml/bag

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.