Naproxen Tablets (Sodium Naproxen)

Adult dose

1. Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis Adults should take sodium naproxen 275-550mg orally twice daily (every 12 hours). 2. Acute gout As the initial dose, adults should take 825mg orally and then continue with 275mg orally every 8 hours until the attack subsides. 3. Skeletal muscle disorders, postoperative pain, pain after tooth extraction, dysmenorrhea, tendinitis, bursitis Adults should take sodium naproxen as an initial dose of 550mg orally, followed by 275mg every 6-8 hours, ensuring the total daily dosage does not exceed 1350mg. 4. Migraine As the initial dose, adults should take 825mg orally. If necessary, an additional 275-550mg can be taken up to once a day, 30 minutes after the initial dose. Ensure the total daily dosage does not exceed 1350mg. Adjust according to age and symptoms.

This medicine could cause serious side effects such as gastrointestinal bleeding if taken by individuals who regularly consume more than three glasses of alcohol per day, so consultation with a doctor or pharmacist is essential. Additionally, this medicine may affect the cardiovascular system, increasing the risk of myocardial infarction or stroke, so patients with cardiovascular disease or risk factors should be especially cautious. This medicine can cause serious gastrointestinal issues, such as bleeding, ulcers, and perforation, and older adults are at an increased risk, so they should consult healthcare professionals immediately if any symptoms arise. Individuals with specific conditions such as peptic ulcers, severe blood abnormalities, liver dysfunction, heart failure, kidney impairment, and hypertension should not take this medicine. Patients with hypersensitivity or previous allergic reactions to aspirin or similar medications should also avoid this medicine. Patients with a history of peptic ulcers or blood abnormalities, bleeding tendencies, or liver or kidney disorders should use this medicine cautiously, consulting healthcare professionals immediately if any unusual symptoms occur. While taking this medicine, various side effects including headache, nausea, skin rash, difficulty breathing, gastrointestinal discomfort, blood abnormalities, liver and kidney function issues may manifest, and in case of such symptoms, immediate discontinuation and physician consultation are advised. During pregnancy, especially in late stages, it may harm the fetus, so its use should be avoided, and breastfeeding women should refrain from taking it as it could affect the baby through breast milk. It is advisable not to administer this medicine to children, especially infants under 2 years, as safety has not been established. Elderly patients are at higher risk of side effects, so it should be used with utmost caution and at minimal doses. This medicine may interact with other non-steroidal anti-inflammatory drugs or specific medications, so any concurrent medications must be communicated to healthcare professionals. In case of overdose, symptoms such as drowsiness, dyspepsia, and vomiting may occur, which necessitates immediate medical attention.

Serious side effects

• Hives
• severe swelling (edema)
• chest tightness
• difficulty breathing
• cold sweat
• pallor
• hematemesis
• gastrointestinal bleeding
• gastric ulcers
• perforation

Mild side effects

• Itching
• rash
• gastrointestinal discomfort
• abdominal pain
• nausea
• vomiting
• loss of appetite
• dyspepsia
• heartburn
• diarrhea

Drug interactions

Do not take this medicine with other non-steroidal anti-inflammatory drugs, naproxen derivatives, aspirin, or high doses of methotrexate. Avoid concurrent use with hydantoins, sulfa drugs, sulfonylureas for lowering blood sugar, propranolol and other beta-blockers, ACE inhibitors (such as captopril), loop diuretics, thiazide diuretics, probenecid, lithium, low-dose methotrexate, coumarin anticoagulants (like warfarin), and others.

This medicine should be stored in a tightly sealed container to prevent air and moisture from entering, at a temperature between 1°C to 30°C. Proper storage helps maintain the drug's effectiveness over time.

Appearance

Blue oval film-coated tablets

Package unit

10 tablets (10 tablets/PTPx1)