Anicru Duo Syrup (Amoxicillin Hydrate · Potassium Clavulanate)

Adult dose

For recurrent tonsillitis and other mild to moderate infections, amoxicillin/clavulanate potassium of 25 mg/3.6 mg per kg body weight is taken twice daily. For severe infections such as otitis media and sinusitis, amoxicillin/clavulanate potassium of 45 mg/6.4 mg per kg body weight is taken twice daily. Administer early in the meal to minimize potential gastrointestinal intolerance.

Child dose

The 7:1 syrup is unsuitable for infants under 2 months and pediatric patients with kidney failure.

This drug contains the artificial sweetener aspartame and should not be administered to patients with phenylketonuria. Care must be taken to not exceed the daily allowable intake of aspartame. This drug is contraindicated for patients with hypersensitivity to its ingredients or beta-lactam antibiotics, patients with infectious mononucleosis or lymphocytic leukemia, a history of liver dysfunction, and patients with lactose intolerance or galactose absorption disorders. Patients with impaired liver or kidney function, allergic constitution, elderly patients, and those with gastrointestinal diseases should use this drug cautiously and be alert for symptoms of vitamin K deficiency. During treatment, gastrointestinal adverse reactions such as diarrhea, abdominal pain, and vomiting may occur, and if severe abdominal pain or blood stools appear, the medication should be discontinued immediately and medical consultation should be sought. Liver function abnormalities, skin rash, hypersensitivity, and hematological abnormalities may rarely occur, so immediate reporting to a medical institution is necessary if these symptoms arise. The prolonged use of this drug may lead to the development of resistant bacteria; therefore, it should be taken for the minimum duration prescribed by a doctor. Severe allergic reactions such as anaphylactic shock may occur, so the patient's condition should be closely monitored after administration and emergency preparedness is required. Pregnant women should preferably avoid this drug, especially in the first trimester, and nursing mothers should be cautious of adverse reactions in their infants. Children and the elderly should be monitored for safety and side effects closely, and safety has not been established for premature and newborn infants. This drug may interact with other medications, so it is essential to inform healthcare professionals of any other medications being taken. In case of overdose, symptoms may include vomiting, diarrhea, kidney failure, and seizures; immediate cessation of the drug and appropriate treatment at a medical facility are required. When storing, keep in a tightly sealed container to prevent exposure to air or moisture. The appropriate storage temperature is cool, between 1 degrees to 25 degrees Celsius, ensuring the effective preservation of the medication.

Serious side effects

Urticaria, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweats, pallor, anaphylaxis, Stevens-Johnson syndrome (skin and mucous membrane disorders), shock, severe rash with high fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, jaundice of skin or eyes, hepatitis, cholestatic jaundice, sudden and severe headache, thunderclap headache, seizures, confusional state, visual disturbances, paralysis, significant decrease in urine output

Mild side effects

Diarrhea, pseudomembranous colitis, dyspepsia, stomatitis, gastritis, glossitis, nausea, vomiting, loss of appetite, abdominal pain, abdominal bloating, constipation, colonic pain, hyperacidity, soft stools, dry mouth, blood in stool, candidiasis, dermatitis, oral edema, itching, erythema multiforme, serum sickness syndrome (fever, rash, arthralgia, edema, lymphadenopathy), eosinophilia, systemic symptoms, angioedema, thrombocytopenia, leukemia, agranulocytosis, lymphocytopenia, thrombocythemia

This drug should be stored in a tightly sealed container to protect it from air and moisture. The storage temperature should be cool, between 1 degree and 25 degrees Celsius, to safely maintain the drug's efficacy.

Appearance

A whitish powder with a peculiar smell, used as a syrup that dissolves before use

Package unit

50mL/bottle