Tobramycin-Dexamethasone Eye Drops

Adult dosage

Administer 1-2 drops into the conjunctival sac every 4-6 hours. Initially, for the first 24-48 hours, administer 1-2 drops every 2 hours and gradually reduce as symptoms improve. Do not stop using it early.

This medication should not be used in patients with viral keratitis, vaccinia, chickenpox, ocular tuberculosis, or fungal diseases of the eye. Additionally, it is not safe for individuals with an allergic reaction to this medication, or for children and breastfeeding individuals. Local side effects such as eyelid itching, swelling, and conjunctival hyperemia may occur during use. Rarely, serious eye diseases such as optic nerve damage, glaucoma, or cataracts may appear. Caution is necessary when used in conjunction with other aminoglycoside antibiotics, monitoring serum concentrations closely, and immediately discontinuing use if adverse reactions occur. Steroid components may worsen an acute purulent eye infection, so caution is advised. Prolonged use may increase the risk of fungal infections of the cornea or secondary bacterial infections, requiring ongoing observation. Overuse may result in symptoms such as punctate keratitis, erythema, edema, eyelid itching, and increased tearing. Vision disturbances like blurred vision may occur; if such symptoms appear, consult an ophthalmologist immediately. Prolonged use may allow the proliferation of fungi or resistant bacteria and requires caution, with proper treatment being necessary for reinfection. Using systemic or localized corticosteroids may result in visual disturbances, so evaluation by a specialist is required if blurred vision or changes in vision occur. During pregnancy, safety has not been fully established and should only be used if the benefits of treatment outweigh the risks. Safety and efficacy in children have not been established, and use is best avoided. This medication should not be injected directly into the eye and should only be used as an eye drop, ensuring that the tip of the container does not come into contact with the eye during use. To prevent contamination, personal use is recommended, avoiding shared use. This medication should be kept out of reach of children and stored in a cool, dry place away from direct sunlight. It should not be transferred to another container, and it is important to confirm any history of infection with chickenpox or measles before administration. Patients with no history of chickenpox or measles or who have not been vaccinated should be particularly cautious to prevent infection, and if infection is suspected or occurs, immediate medical attention is needed. Even if there is a history of chickenpox or measles, care must be taken as the possibility of infection during use exists; ongoing careful observation is required.

Serious side effects

• Optic nerve damage
• decreased vision and field of vision
• cataract formation
• eyeball perforation
• severe swelling (eyelid swelling)
• and vision abnormalities.

Mild side effects

• Eyelid itching
• swelling
• conjunctival redness
• punctate keratitis
• erythema
• increased lacrimation
• blurred vision
• acute purulent eye infection
• corneal fungal infection
• secondary bacterial infections

This medication may be degraded by air or light, so it should be stored in a sealed container. Additionally, it should be stored away from direct sunlight at a temperature between 1 to 30 degrees Celsius.

Appearance

A white suspension in a clear plastic container

Package unit

5mL/bottle x 1 bottle/carton