Medication info

Duo Cream Dry Syrup (Amoxicillin-Potassium Clavulanate (7:1))

Prescription medicationSyrup경구Approval withdrawn
Ingredient · strength
Amoxicillin Hydrate›36.326g / 100gDilute Potassium Clavulanate›10.352g / 100g
Manufacturer / importer
고려제약(주)
Appearance
A white or pale yellow powder to be dissolved in water to prepare syrup
Packaging
50mL/bottle×40, 50mL/bottle
Approval status
Approval withdrawn

MFDS item code 200201777 · Notified 2002.07.22

This product's status changed to Approval withdrawn on 2025.03.28. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Treatment of infections in the respiratory system (bronchitis, pneumonia) and urinary tract (cystitis, urethritis)
Who takes it
Adults · Children
Adult dose
For mild to moderate infections of the upper respiratory tract such as recurrent tonsillitis, lower respiratory tract infections, urinary tract infections, and skin/soft tissue infections, amoxicillin/potassium clavulanate is taken in divided doses of 25 mg/3.6 mg per kg of body weight, twice a day. For severe infections such as otitis media, sinusitis of the upper respiratory tract, bronchial pneumonia of the lower respiratory tract, and urinary tract infections, it is taken in divided doses of 45 mg/6.4 mg per kg of body weight, twice a day. Potentially
Child dose
The 7:1 syrup is not suitable for children under 2 months old. Pediatric patients with kidney failure are not suitable for the 7:1 syrup. The dosage is 25 mg/3.6 mg or 45 mg/6.4 mg per kg of bodyweight to be divided into 2 doses.

Ingredients

Manufacturer
고려제약(주)

Efficacy & effects

Treatment of infections in the respiratory system (bronchitis, pneumonia) and urinary tract (cystitis, urethritis)

  • Acute and chronic bronchitis
  • lobar pneumonia
  • bronchial pneumonia
  • empyema
  • lung abscess
  • tonsillitis
  • sinusitis
  • otitis media
  • cystitis
  • urethritis
  • pyelonephritis
  • pelvic inflammatory disease
View approved original text

This medication is effective in treating infections caused by various bacteria. It treats respiratory infections such as acute and chronic bronchitis, lobar and bronchial pneumonia, empyema, lung abscess, tonsillitis, sinusitis, and otitis media. It is also used for urinary infections such as cystitis, urethritis, and pyelonephritis. It is reassuring to know that it is effective against sexually transmitted infections like pelvic inflammatory disease and gonorrhea. Additionally, it aids in the treatment of skin abscesses, pyogenic infections, soft tissue infections, wound infections, and osteomyelitis. Finally, it is used to treat dental infections, thus improving bacterial infections in various areas.

How to take

Adult dose

For mild to moderate infections of the upper respiratory tract such as recurrent tonsillitis, lower respiratory tract infections, urinary tract infections, and skin/soft tissue infections, amoxicillin/potassium clavulanate is taken in divided doses of 25 mg/3.6 mg per kg of body weight, twice a day. For severe infections such as otitis media, sinusitis of the upper respiratory tract, bronchial pneumonia of the lower respiratory tract, and urinary tract infections, it is taken in divided doses of 45 mg/6.4 mg per kg of body weight, twice a day. Potentially

Child dose

The 7:1 syrup is not suitable for children under 2 months old. Pediatric patients with kidney failure are not suitable for the 7:1 syrup. The dosage is 25 mg/3.6 mg or 45 mg/6.4 mg per kg of bodyweight to be divided into 2 doses.

Precautions

This medication, being a beta-lactam antibiotic, should not be used in patients with hypersensitivity to its components or other penicillin-related drugs. It should be particularly avoided in patients with infectious mononucleosis or lymphocytic leukemia due to a high risk of rash. Caution is also needed in patients with a history of liver dysfunction or jaundice. Patients with impaired liver or kidney function, those with allergies, the elderly, and patients with gastrointestinal disorders should be administered with caution, and dosage adjustments may be required. Gastrointestinal side effects may arise, such as diarrhea, vomiting, and abdominal pain, and if symptoms are severe, it is crucial to consult a healthcare professional immediately. Symptoms of liver dysfunction may also occur, thus regular liver function tests are advisable. In case of serious allergic reactions like skin rash, urticaria, or anaphylaxis, treatment should be stopped immediately and emergency measures should be taken. Rarely, abnormalities in the blood system or kidney function have been reported, so it is important to inform the healthcare team of any symptoms. Serious gastrointestinal conditions, such as pseudomembranous colitis, may occur during antibiotic use, so if diarrhea or abdominal pain worsens, medication should be stopped immediately. As this medication may interact with other drugs, it is essential to inform the healthcare team of any other medications being taken. Women who are pregnant or breastfeeding should consider the effects on the fetus or infant and make a cautious decision regarding use. The safety of this medication has not been established in children, especially neonates under 2 months old. The elderly are at higher risk of side effects due to decreased bodily functions, so dosage and administration intervals should be adjusted and monitored. This medication should be stored under refrigeration and used within 7 days after preparation. In case of overdose, symptoms such as vomiting, diarrhea, kidney failure, and seizures may occur, requiring immediate treatment at a medical facility.

Side effects and when to seek care immediately

Serious side effects

Urticaria, severe swelling (edema), tightness in the chest, difficulty breathing, cold sweat, paleness, severe allergic reactions, high fever accompanied by severe rashes, blisters, shedding skin, pain in mucous membranes of the mouth/eyes, severe skin adverse reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanying cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, liver abnormalities (jaundice), sudden and

Mild side effects

  • Diarrhea
  • indigestion
  • stomatitis
  • gastritis
  • glossitis
  • nausea
  • vomiting
  • loss of appetite
  • abdominal pain
  • abdominal distension
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  • constipation
  • colonic pain
  • acid reflux
  • changes in stool
  • dry mouth
  • acute pancreatitis
  • candidiasis
  • blood in stool
  • itching
  • erythema multiforme
  • dermatitis
  • oral edema
  • restlessness
  • anxiety
  • behavioral changes
  • confusion
  • drowsiness
  • insomnia
  • hyperactivity
  • dizziness
  • headache
  • seizures
  • mucosal candidiasis
  • vaginal itching/burning
  • increased discharge
  • vitamin K deficiency symptoms

Not everyone experiences these, and they can vary from person to person.

Storage

This medication must be stored in a tightly sealed container to prevent exposure to air or moisture. Additionally, it is recommended to store it in a cool, dry place under 25 degrees Celsius. By following this storage advice, the medicinal effects can be maintained for a longer period.

Appearance and packaging

Appearance

A white or pale yellow powder to be dissolved in water to prepare syrup

Package unit

50mL/bottle×40, 50mL/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.