DUOnex Dry Syrup [(Amoxicillin, Clavulanate Potassium (7:1)]

Adult dose

For mild to moderate infections such as recurrent tonsillitis, upper respiratory infections, lower respiratory infections, urinary tract infections, and skin and soft tissue infections, amoxicillin/clavulanate potassium is typically dosed at 25 mg/3.6 mg per kg of body weight, divided into two doses per day. For severe infections like otitis media, sinusitis, bronchopneumonia, and urinary tract infections, the dosage is typically 45 mg/6.4 mg per kg of body weight, divided into two doses per day.

Child dose

The 7:1 syrup is not suitable for infants under 2 months of age and is also not suitable for pediatric patients with renal failure. The dosage is divided into two doses per day based on weight in kg.

This medication is a beta-lactam antibiotic and should not be administered to patients with a history of allergic reactions to penicillin-based medications. Special caution is necessary for patients with infectious mononucleosis or lymphocytic leukemia, as they have an increased risk of rash. This drug should be used cautiously in patients with impaired liver or kidney function, as they may experience worsening of liver or kidney issues, requiring regular monitoring. Patients with an allergic constitution or a history of symptoms such as bronchial asthma, rash, or urticaria should also take caution. Gastrointestinal side effects such as diarrhea, vomiting, and abdominal pain may occur, so it is advisable to take this medication with meals to reduce gastrointestinal side effects. Liver function issues, and rarely hepatitis or jaundice, may appear, so immediate consultation with healthcare professionals is necessary if symptoms occur. Severe skin reactions such as rash, itching, or serious conditions like Stevens-Johnson Syndrome may occur; if any abnormal symptoms appear, discontinue use. Blood-related anomalies such as leukopenia, anemia, or thrombocytopenia may be reported occasionally, making regular blood tests necessary. Central nervous system symptoms such as headaches, dizziness, or seizures may rarely occur, so monitoring for these symptoms is essential. In cases of overdose, symptoms like vomiting, diarrhea, or renal failure may occur, and immediate medical attention should be sought. During pregnancy or breastfeeding, it should be used cautiously only when necessary, especially during the early three months of pregnancy. Elderly patients may have an increased risk of adverse reactions due to impaired kidney and liver function, requiring careful adjustment of dosage and intervals. This medication can interact with other drugs, so inform healthcare professionals about any medications being taken. If diarrhea, abdominal pain, rash, or any other abnormal symptoms occur during treatment, consult a physician immediately, and after preparation, store it in the refrigerator and use within 7 days.

Serious side effects

Urticaria, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rash with high fever, blisters, peeling skin, painful mucosa in mouth/eyes, severe skin adverse reactions, difficulty breathing or wheezing, asthma attacks, respiratory abnormalities accompanied by coughing and fever, yellowing of the skin or eyes, extreme lethargy, hepatic abnormalities (jaundice), sudden and severe headaches, and com

Mild side effects

Diarrhea, indigestion, stomatitis, gastritis, glossitis, nausea, vomiting, loss of appetite, abdominal pain, abdominal bloating, constipation, colonic pain, gastric acid secretion, loose stools, dry mouth, acute pancreatitis, candidiasis, blood in stools, membranous colitis, elevated AST, ALT, ALP, LDH, raised serum bilirubin, hepatitis, cholestatic jaundice, itching, erythema multiforme, mucous membrane syndrome, toxic epidermal necrolysis, vesicular exfoliative dermatitis, acute generalized exanthematous pustulosis, ho

This medication should be stored in a tightly closed container to protect it from air and moisture. To maintain the potency of the medication, it is crucial to store it in a cool, dry place at a temperature below 25 degrees Celsius.

Appearance

A white or pale yellow powder that is reconstituted into a syrup before use

Package unit

50ml/bottle, 500ml/bottle