Latrol Injection (Tramadol Hydrochloride)

Adult administration

As tramadol hydrochloride, administer 50-100mg by intravenous or intramuscular injection and repeat every 4-5 hours as needed. The maximum daily dosage can be up to 400mg.

This medication can cause seizures if used above the recommended dosage, so it must be used with caution in patients at risk of seizures. Additionally, long-term use may lead to psychological and physical dependence, so it should be administered only for a short period under strict supervision in patients at risk of drug abuse. It can cause severe drowsiness, respiratory depression, coma, and in severe cases, death when taken with central nervous system depressants or alcohol, so extreme caution is required when used together. Patients who genetically metabolize this drug quickly may have increased blood levels of active metabolites, raising the risk of respiratory depression; therefore, dosage adjustment or alternative medications may be necessary for these patients. This medication should not be administered to children under 12 years of age or adolescents under 18 years of age who have undergone tonsillectomy or adenoidectomy, and in adolescents aged 12 to 18, it should be avoided if there are special risk factors. It should not be used in patients with acute alcohol intoxication, central nervous system drug intoxication, severe respiratory depression, head injury or brain lesions, those taking MAO inhibitors, severe liver or kidney dysfunction, pregnant women, or nursing mothers. This medication may have interactions that exacerbate side effects when taken with other analgesics or central nervous system depressants. When co-administered, dosage should be reduced, and patient conditions should be closely monitored. During treatment, drowsiness and dizziness may occur; thus, driving or operating dangerous machinery should be avoided, and tolerance may develop, leading to a gradual increase in dosage which could cause withdrawal symptoms if abruptly discontinued. In case of overdose, severe respiratory depression and seizures may occur, requiring immediate emergency treatment, and if necessary, administration of antidotes and maintenance of respiratory and cardiovascular functions. This medication should be stored out of reach of children, and kept in the original container to prevent drug misuse and deterioration of quality.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweats, paleness, severe rash with high fever, blisters, peeling skin, pain in mouth/eye mucosa, severe skin reactions, asthma attacks, respiratory abnormalities accompanied by coughing and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, liver abnormalities, sudden and very severe headaches, lightning headaches, seizures, altered consciousness, visual disturbances,

Mild side effects

• Drowsiness
• dizziness
• nausea
• vomiting
• abdominal distension
• abdominal pain
• loss of appetite
• constipation
• thirst
• hypertonia

This medication should be stored in a sealed container to prevent air or moisture from entering. It is best to maintain a storage temperature between 1 and 30 degrees Celsius at room temperature. Storing it this way will help maintain the drug's efficacy and safety.

Appearance

Colorless and transparent ampoule containing a colorless liquid

Package unit

Domestic use - 1 milliliter/ampoule [×50 ampoules], Export use - 1 milliliter/ampoule [×10 ampoules], Export use - 2 milliliters/ampoule [×10 ampoules]