Ogumacjeong 625mg [Amoxicillin and Clavulanate Potassium (4:1)]

Adult dose

Adults and children aged 12 years or older or weighing 40 kg or more should take 250 mg/125 mg of amoxicillin/clavulanate potassium orally three times a day every 8 hours. In case of severe or respiratory infections, the dosage can be increased to 500 mg/125 mg. In cases of renal impairment, dosage should be adjusted according to creatinine clearance, if the creatinine clearance is 10 to 30 mL/min, administer 250 mg.

Child dose

Adults and children aged 12 years or older or weighing 40 kg or more are included, other children can be dosed using the same method with reduced amounts.

This medication is a beta-lactam antibiotic, and should not be taken by individuals allergic to penicillin or cephalosporin drugs. Particularly, caution is needed for patients with infectious mononucleosis or lymphocytic leukemia due to the increased risk of rash. Those with poor liver function or a history of liver dysfunction or jaundice due to this medication or penicillin should avoid or use it with caution. In cases of moderate to severe renal impairment, dosage intervals should be adjusted, and caution should be used for allergic individuals, elderly patients, or those in poor general condition. Gastrointestinal symptoms such as diarrhea, vomiting, and abdominal pain may occur; if severe diarrhea or blood in stools occurs, stop taking the medication and consult a doctor immediately. Rarely, hypersensitivity reactions such as abnormal liver enzymes, hepatitis, and skin rashes may arise, and any unusual symptoms should be reported immediately. Regular blood tests may be necessary to monitor for changes such as leukopenia or thrombocytopenia. Pregnant women in early pregnancy or breastfeeding women must consult a doctor before taking this medication, and caution is advised during breastfeeding as it may affect the baby. For children, it is recommended to administer only to those aged 12 years or older or weighing over 40 kg; caution is necessary as there is limited experience with pediatric use. Elderly patients may experience side effects more readily due to decreased kidney function; thus, dosage and intervals should be adjusted and their condition monitored. There may be interactions when taken with other medications, so it is essential to inform the doctor of any other medications being taken, particularly when used with anticoagulants or certain antibiotics. In case of overdose, symptoms may include vomiting, diarrhea, rash, and renal failure; if symptoms are severe, seek medical attention immediately. This medication should be stored in a dry place below 25 degrees Celsius, and it is vital to take it for the minimum period as directed by a physician to prevent resistance.

Serious side effects

Urticaria, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, anaphylaxis, mucocutaneous syndrome, shock, severe allergic reactions, high fever with severe rash, blisters, skin peeling, pain in oral/ocular mucosa, severe skin reactions, shortness of breath or difficulty breathing, asthmatic attacks, respiratory distress with coughing and fever, jaundice (yellowing of skin or eyes), feeling extremely fatigued, liver dysfunction (jaundice)

Mild side effects

Diarrhea, pseudomembranous colitis, indigestion, stomatitis, gastritis, glossitis, black hairy tongue, nausea, vomiting, loss of appetite, abdominal pain, abdominal bloating, constipation, colonic pain, acid reflux, soft stools, xerostomia, acute pancreatitis, candidiasis, colitis, bloody stools, itching, erythema multiforme, rash, dermatitis, serum sickness, arthralgia, edema, lymphadenopathy, bronchospasm, cutaneous reactions controlled by systemic corticosteroids, reversible leukopenia, blood

This medication should be stored in a tightly closed container to prevent moisture and kept in a dry place. Additionally, the storage temperature should be maintained between 1 and 25 degrees Celsius. This ensures that the medication effectiveness is preserved and deterioration is prevented.

Appearance

Oval film-coated tablet, white to almost white

Package unit

30 tablets/box [(6 tablets x 5 PTP)], 120 tablets/box [(30 tablets/box x 4)]