OguMac Duo Dry Syrup (Amoxicillin. Clavulanate Potassium (7:1))

Adult dose

For mild to moderate infections such as recurrent tonsillitis, upper respiratory infections, lower respiratory infections, urinary tract infections, and skin/soft tissue infections, take 25 mg/3.6 mg per kg of body weight twice daily. For moderate to severe infections such as otitis media, sinusitis, bronchopneumonia, and urinary tract infections, take 45 mg/6.4 mg per kg of body weight twice daily. To minimize potential gastrointestinal intolerance, it is recommended to take it at the beginning of meals.

Child dose

The 7:1 syrup is not suitable for children under 2 months of age. In pediatric patients with renal failure, the 7:1 syrup is not suitable.

This medication contains amoxicillin and clavulanate potassium, which are penicillin-type antibiotics. Do not take this medication if you have had allergic reactions to any component of this product or to beta-lactam antibiotics. Additionally, caution is advised if there are concurrent viral diseases such as infectious mononucleosis or lymphocytic leukemia, as the risk of adverse reactions such as rashes is increased. Patients with liver function problems should also be cautious as this medication may worsen liver function. For patients with moderate to severe impaired renal function, the dosing interval should be adjusted to prevent accumulation in the body. Patients with allergic tendencies or those experiencing symptoms like bronchial asthma, rashes, and hives should exercise caution. Gastrointestinal symptoms like diarrhea, abdominal pain, vomiting, and loss of appetite may occur. In severe cases, pseudomembranous colitis or acute pancreatitis may develop, requiring immediate discontinuation and consultation with a physician if unusual symptoms arise. Liver function abnormalities may occur, particularly among the elderly or males, with severe cases leading to hepatitis or jaundice. Rarely, skin rashes, itching, severe skin reactions (such as Stevens-Johnson syndrome), or anaphylactic shock may occur. Seek immediate medical attention if skin symptoms or difficulty in breathing develop. Blood tests may reveal rare cases of leukopenia, thrombocytopenia, or hemolytic anemia, necessitating vigilance for bleeding symptoms. This medication may occasionally cause fungal infections such as oral candidiasis or vaginitis; inform your healthcare provider if these symptoms occur. Central nervous system symptoms like dizziness, headaches, or seizures may rarely appear, particularly in patients with impaired renal function or when given in high doses. Pregnant women should avoid taking this medication, especially during the first three months, and breastfeeding mothers should observe for any adverse reactions in the infant. Safety for neonates under 2 months, particularly premature infants, has not been established. Elderly patients may manifest adverse reactions more readily due to declining physical function; therefore, dosage and intervals should be adjusted and monitored closely. This medication may interact with other drugs, so inform your doctor or pharmacist, especially if you are taking anticoagulants, other antibiotics, or anti-inflammatory medications. In case of overdose, symptoms may include vomiting, diarrhea, rash, drowsiness, and seizures, necessitating immediate discontinuation and appropriate treatment at a medical facility. This medication should be refrigerated after preparation and used within 7 days; it should be shaken well before use. Finally, this medication should only be taken for the duration prescribed by your doctor to prevent the emergence of resistant bacteria; do not discontinue use without consulting a physician, even if symptoms improve.

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, paleness, severe allergic reactions, high fever with severe rash, blisters, skin peeling, pain in the mouth/eyes mucosa, severe adverse skin reactions, shortness of breath, asthma attacks, respiratory disturbances accompanied by cough and fever, breathing problems, yellowing of the skin or eyes, significant fatigue, liver abnormalities, sudden and severe headaches, or migraines.

Mild side effects

• Diarrhea
• pseudomembranous colitis
• indigestion
• stomatitis
• gastritis
• glossitis
• black hairy tongue
• nausea
• vomiting
• loss of appetite

This medication should be stored in a tightly sealed container to prevent air or moisture ingress. It is best kept in a cool place between 1°C and 25°C, avoiding extremes of heat or cold.

Appearance

A white or pale yellow powder that is dissolved before use as syrup

Package unit

5.5g(50mL)/bottle x 10 bottles