Tralin Tablets 50 mg (Sertraline Hydrochloride)

Adult dosage

Depression and obsessive-compulsive disorder: Start with a dose of 50 mg of sertraline once daily. The maintenance dose is 50-100 mg daily. If the effect is insufficient, the dose may be increased by 50 mg up to a maximum of 200 mg daily, with dose adjustments made at least 1 week apart. Panic disorder, post-traumatic stress disorder, and social anxiety disorder: Start with a dose of 25 mg once daily.

Children's dosage

Obsessive-Compulsive Disorder: For patients aged 6-12 years, start with a dose of 25 mg once daily; for patients aged 13-17 years, start with a dose of 50 mg once daily. Children aged 6-17 with obsessive-compulsive disorder can be given a dose of 25-200 mg/day.

This medication is primarily used as an antidepressant for the treatment of psychiatric disorders such as depression and obsessive-compulsive disorder. When taking this medication, the risk of suicidal thoughts or behaviors may increase, especially in young patients aged 18 to 24, so careful assessment of the need for treatment and associated risks by a doctor is required. There is a risk of a serious side effect known as serotonin syndrome, which may include symptoms such as agitation, hallucinations, fever, tremors, nausea, and vomiting, and the risk increases when taken with other serotonergic medications. It should not be taken with certain medications known as MAO inhibitors, as this can lead to life-threatening side effects. Patients with moderate to severe liver impairment, those allergic to this medication, and those with certain heart conditions should not take this medication. Patients with epilepsy or mild liver impairment should be closely monitored as there is a risk of seizures when taking this medication. This medication can cause various side effects such as drowsiness, dizziness, headache, dyspepsia, insomnia, anxiety, and in severe cases, may include cardiac rhythm abnormalities or skin rashes. Particular caution should be exercised while driving or operating machinery as this medication may impair concentration. Discontinuation of this medication should be gradual to avoid withdrawal symptoms such as dizziness, anxiety, and sleep disturbances, so dosage must be decreased gradually according to a physician's instructions. Pregnant or breastfeeding women should carefully consider the potential effects of this medication on the fetus or newborn, weighing the benefits and risks of treatment. It is not recommended for use in children and adolescents for indications other than obsessive-compulsive disorder, and growth and development monitoring is necessary. When used in conjunction with other medications, potential interactions may occur, so consultation with a doctor or pharmacist is essential, especially when taking medications affecting blood coagulation or other psychiatric medications. In cases of overdose, severe side effects may occur, requiring immediate medical attention, as specific antidotes are not available, making symptomatic treatment important. This medication should be kept out of reach of children, and transferring it to other containers should be avoided to maintain quality.

Serious side effects

Hives, angioedema, severe swelling (including facial edema, peripheral edema), chest tightness, difficulty breathing, autonomic nervous instability (tachycardia, unstable blood pressure, dizziness, sweating, flushing, high fever), serotonin syndrome, neuroleptic malignant syndrome, severe skin reactions (severe rash, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, toxic epidermal necrolysis, Stevens-Johnson syndrome, exfoliative dermatitis, photosensitivity skin reactions), liver abnormalities (liver

Mild side effects

• Insomnia
• depressive symptoms
• decreased libido
• agitation
• anxiety
• hallucinations
• aggression
• euphoria
• confusion
• teeth grinding

This medication should be stored in a tightly closed container to protect it from air and moisture. It is advisable to maintain a storage temperature between 1°C and 30°C. This helps preserve the medication's effectiveness for a longer period.

Appearance

White, rectangular film-coated tablet

Package unit

30 tablets/bottle, 200 tablets/bottle