Simvatin Tablets 40 mg (Simvastatin)

Adult dose

This medication is taken once daily in the evening. 1. For the reduction of cardiovascular disease risk, the recommended initial starting dose is 40 mg once daily. 2. For hyperlipidemia, the general initial starting dose is 20 mg once daily in the evening, and patients with mild to moderate hypercholesterolemia may start with 10 mg. The dosage can be administered once daily in the evening at 5–40 mg, and prior to administering, LDL cholesterol levels should be assessed.

Child dose

The recommended initial dosage for pediatric patients (ages 10–17) with heterozygous familial hypercholesterolemia is 10 mg once daily in the evening. The recommended dosing range is 10–40 mg once daily, with a recommended maximum dose of

This drug can cause muscle problems; therefore, if muscle pain or weakness is experienced, the doctor must be notified immediately. Particularly, if taking high doses, the risk of muscle damage is higher, and caution is necessary. Patients who are allergic to this drug or have severely impaired liver function, as well as women who are pregnant or breastfeeding, should not take it. Additionally, if taken with certain medications, the risk of side effects may increase; thus, if taking other medications, it is essential to inform a doctor or pharmacist. Patients with poor liver function or those who consume alcohol heavily should have their liver function checked regularly while using this drug. This drug is not used in children under 10 years of age or premenarche females. Elderly patients, women, patients with hypothyroidism, and patients with impaired renal function should exercise greater caution when taking this medication. If unexplained muscle pain or weakness occurs during treatment, consult medical staff immediately, and if necessary, medication can be discontinued. This drug can affect the fetus during pregnancy, so it must be stopped immediately if pregnancy is confirmed. It is also advisable to avoid certain foods such as grapefruit juice during use. In case of overdose, immediate medical attention should be sought for appropriate treatment. This medication should be kept out of reach of children and stored in its original container for safety.

Serious side effects

Rhabdomyolysis, severe myopathy, anaphylaxis, angioedema, severe allergic reactions, severe rashes, blisters, skin peeling, pain in oral/ocular mucosa, Stevens–Johnson syndrome, toxic epidermal necrolysis, severe skin adverse reactions, difficulty breathing or shortness of breath, asthma attacks, respiratory issues accompanied by cough and fever, jaundice, liver abnormalities, hepatitis, fatal or non-fatal liver failure, fulminant hepatic necrosis, severe liver damage, sudden

Mild side effects

• Abdominal pain
• weakness
• constipation
• diarrhea
• indigestion
• bloating
• nausea
• headache
• upper respiratory infection
• atrial fibrillation

This medication must be stored in a tightly closed container to prevent air or moisture from entering, and it should be kept at room temperature between 1 degree and 30 degrees Celsius. Storing it this way helps maintain the medication's effectiveness.

Appearance

Light pink oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle