Husimba Tablet (Simvastatin)

Adult dose

For adult patients, the recommended initial starting dose of simvastatin is 40 mg once daily. For patients with hypercholesterolemia with coronary heart disease, the generally recommended starting dose is 20 mg taken once in the evening. Mild to moderate hypercholesterolemia patients may start with 10 mg. The dose is administered once daily in the evening at 5-40 mg, and prior to administration should check the LDL

Child dose

For pediatric patients aged 10-17 years, the recommended initial dose is 10 mg taken once daily in the evening. The recommended dosage range is 10-40 mg per day, with a maximum dose of 40 mg per day. The administration dose may adjust according to treatment goals.

This medication can cause myopathy or rhabdomyolysis. The risk is particularly higher when taking a high dose of 80 mg, so caution is needed. Patients with an allergy to this medication, severely impaired liver function, pregnant or nursing women, and those taking it with certain strong medications should not use this medication. Patients with weakened liver or kidney function, hypothyroidism or a history of muscle disease, elderly patients, and women should be more cautious when taking this medication. If muscle pain, weakness, or unusual symptoms occur during treatment, immediately inform a doctor and discontinue the medication if necessary. This medication may affect liver function, so regular liver function tests are important. If any symptoms of liver dysfunction occur, consult a medical professional immediately. This medication can interact with other drugs, so it is essential to discuss with a doctor, especially when taking certain antibiotics, antifungals, immunosuppressants, calcium channel blockers, nicotinic acid, etc., and adjustments in dosage or discontinuation may be needed. Pregnant women or those who may become pregnant should strictly avoid taking this medication, and if pregnancy is confirmed while on the medication, it should be stopped immediately and consultation with a healthcare professional is necessary. Nursing mothers are advised to discontinue breastfeeding while taking this medication. The use of this medication is limited in children and adolescents, especially it is not safe for patients under 10 years old. Elderly patients may have higher blood concentrations of this medication, so dosage adjustments and monitoring for side effects are required. Excessive intake of grapefruit juice or grapefruit products should be avoided while on this medication, as it may increase the medication’s concentration and raise the risk of side effects. Patients taking this medication must inform their healthcare provider when being prescribed new medications. In case of overdose, general emergency treatments should be performed, and since there is no specific antidote, immediate medical attention is required. Keep out of reach of children, and store in the original container to prevent misuse and degradation of the medication's quality.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain of mucous membranes in the mouth/eyes, difficulty breathing or shortness of breath, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), profound malaise, sudden and severe headache, thunderclap headaches, seizures, confusion, vision changes, paralysis, urination problems

Mild side effects

Abdominal pain, fatigue, constipation, diarrhea, dyspepsia, bloating, nausea, headache, upper respiratory infection, atrial fibrillation, gastritis, diabetes, myalgia, insomnia, dizziness, bronchitis, sinusitis, eczema, urinary tract infection, alopecia, pruritus, various skin changes, lichenoid drug rash, gynecomastia, decreased libido, sexual dysfunction, progression of cataracts, eye muscle paralysis, anemia, thyroid dysfunction, transient and mild liver function test abnormalities, H

This medication can be sensitive to air or moisture, so it must be stored in a tightly sealed container. It is recommended to maintain a storage temperature between 1°C and 30°C to safely preserve the medication's efficacy.

Appearance

Brownish yellow oval film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle