Medication info
Mevalochin Tablet 20 milligrams (Pravastatin Sodium)

Mevalochin Tablet 20 milligrams (Pravastatin Sodium)

Prescription medicationTablet경구
Ingredient · strength
Pravastatin Sodium›20mg / 1 tablet
Manufacturer / importer
에이치케이이노엔(주)
Appearance
Yellowish, oval-shaped tablet with a bisect on both sides
Packaging
100 tablets (10 tablets/PTP packaging x 10)
Approval status
Active

MFDS item code 200200143 · Notified 2002.09.04 · Insurance code 640003800

Summary

Main use
(Hyperlipidemia) Improves blood LDL levels and (Cardiovascular Disease) Reduces the risk of myocardial infarction
Who takes it
Adults
Adult dose
Prior to initiating treatment, the patient should start a low-cholesterol diet and continue it throughout treatment. The usual starting doses are 10 mg, 20 mg, or 40 mg taken once daily. Depending on the patient's response, the dose may be increased up to a maximum of 40 mg. The maintenance dose is 10-40 mg taken once daily. For patients with a history of myocardial infarction or unstable angina, use a dose of 40 mg/day. In patients receiving immunosuppressants such as cyclosporine,

Ingredients

Manufacturer
에이치케이이노엔(주)

Efficacy & effects

(Hyperlipidemia) Improves blood LDL levels and (Cardiovascular Disease) Reduces the risk of myocardial infarction

  • Primary hyperlipidemia
  • hypercholesterolemia
  • hypertriglyceridemia
  • vascular disease history
  • resting ECG changes
  • diabetes
  • smoking
  • low HDL levels
  • family history of myocardial infarction
  • hypertension
  • myocardial infarction
  • unstable angina
View approved original text

This medication is used for primary hyperlipidemia, which presents as a combination of hypercholesterolemia and hypertriglyceridemia. It also helps reduce the risk of myocardial infarction or mortality due to coronary heart disease in high-risk patients with hypercholesterolemia that is not controlled by diet alone, such as those with a history of vascular disease, diabetes, smokers, and certain age groups. It is effective in reducing the risk of myocardial infarction recurrence, the need for cardiovascular revascularization, ischemic stroke, and transient ischemic attacks in patients with a history of myocardial infarction or unstable angina. It is used to prevent the occurrence and worsening of cardiovascular diseases through these efficacies.

How to take

Adult dose

Prior to initiating treatment, the patient should start a low-cholesterol diet and continue it throughout treatment. The usual starting doses are 10 mg, 20 mg, or 40 mg taken once daily. Depending on the patient's response, the dose may be increased up to a maximum of 40 mg. The maintenance dose is 10-40 mg taken once daily. For patients with a history of myocardial infarction or unstable angina, use a dose of 40 mg/day. In patients receiving immunosuppressants such as cyclosporine,

Precautions

This medication should not be used in patients with hypersensitivity or severe liver disease. It should not be administered to pregnant women or women who may become pregnant, as well as nursing mothers. It is not recommended for use in children due to lack of established safety and efficacy. Patients with severely impaired liver or kidney function should use this medication with caution, and caution is warranted in cases of liver dysfunction, as liver function may deteriorate. Patients with muscle disorders or cholestasis should also avoid using this medication. Since this medication is primarily metabolized in the liver, regular liver function tests should be conducted, and if liver enzyme levels rise, consultation with a physician is necessary. If symptoms such as muscle pain, muscle weakness, or muscle cramps occur, the physician should be notified immediately, as severe muscle damage known as rhabdomyolysis may occur. During the course of taking this medication, blood lipid levels should be monitored regularly to confirm treatment efficacy. The risk of muscle-related side effects may increase when combined with other medications, particularly fibrates, cyclosporine, niacin, and colchicine; thus, caution is necessary. It should also be administered with caution in patients who consume alcohol excessively or have severe myasthenia. Patients should be instructed to immediately inform healthcare personnel if they experience unexplained muscle pain, weakness, or fever while taking this medication. Older adults may have decreased physiological functions, requiring special attention such as dosage adjustment. Pregnant or nursing women should not take this medication and should discontinue it immediately if pregnancy is confirmed during use. In case of overdose, appropriate tests, including liver function tests, may be necessary. This medication is most effective when taken after dinner, and timing adjustments may be necessary when taken with other medications. It should be kept out of the reach of children, and it is advisable not to transfer it to another container.

Side effects and when to seek care immediately

Serious side effects

Hives, angioedema, chest tightness, difficulty breathing, anaphylaxis, thrombocytopenia, leukopenia, hemolytic anemia, vasculitis, lupus-like syndrome, photosensitivity, hypotension, dermatomyositis, severe skin rashes and blisters, skin peeling, mucosal pain in the mouth/eyes, jaundice indicated by yellowing of the skin or eyes due to liver dysfunction, generalized malaise, acute renal failure associated with rhabdomyolysis, severe edema, hypertension, severe musc

Mild side effects

  • Hypersensitivity reactions such as rash
  • itching
  • diarrhea
  • nausea
  • vomiting
  • constipation
  • abdominal pain
  • discomfort in the upper abdomen
  • stomatitis
  • heartburn
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  • abdominal bloating
  • loss of appetite
  • elevated levels of ALT
  • AST
  • ALP
  • LDH
  • γ-GTP
  • total bilirubin
  • BUN
  • serum creatinine
  • muscle pain
  • weakness
  • headache
  • dizziness
  • insomnia
  • peripheral neuropathy
  • depression
  • lethargy
  • fatigue
  • sleep disturbances
  • elevated uric acid
  • hematuria
  • hair loss
  • erectile dysfunction
  • arthritis

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container, protected from air and moisture, and maintained at room temperature. Proper storage can help preserve the medication's effects for a longer period.

Appearance and packaging

Appearance

Yellowish, oval-shaped tablet with a bisect on both sides

Package unit

100 tablets (10 tablets/PTP packaging x 10)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.