Medication info

Zithromax Injection 500 mg (Azithromycin Dihydrate)

Prescription medicationIntravenous injection
Ingredient · strength
Azithromycin Hydrate›524.1mg / 1 vial
Manufacturer / importer
Pfizer Pharmaceuticals Korea Limited
Appearance
A vial filled with white to off-white powder
Packaging
1.107g/vial X 10 vials
Approval status
Active

MFDS item code 200108815 · Approved 2001.07.12 · Insurance code 648900891

Summary

Main use
Treatment of community-acquired pneumonia and pelvic infections
Who receives it
Adults
Adult administration
Community-acquired pneumonia: 500 mg intravenously once daily for at least 2 days, followed by oral azithromycin 500 mg once daily for 5-8 days. Total duration of intravenous and oral administration: 7-10 days Pelvic infection: 500 mg intravenously once daily for 1-2 days, followed by oral administration of 250 mg once daily for 5-6 days. Total duration of intravenous and oral administration: 7 days

Ingredients

Importer
Pfizer Pharmaceuticals Korea Limited

Efficacy & effects

Treatment of community-acquired pneumonia and pelvic infections

  • Community-acquired pneumonia
  • pelvic inflammatory disease
View approved original text

This medication is effective against a variety of bacteria and microorganisms, particularly targeting several pathogens such as Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae, Escherichia coli, and Neisseria gonorrhoeae. It is commonly used to treat community-acquired pneumonia and pelvic inflammatory diseases. This drug helps improve various infection symptoms and eliminates infection causes. Therefore, it could be an effective treatment for those suffering from pneumonia or pelvic infections. It is a medication designed to ensure safe treatment.

How it is given

Adult administration

Community-acquired pneumonia: 500 mg intravenously once daily for at least 2 days, followed by oral azithromycin 500 mg once daily for 5-8 days. Total duration of intravenous and oral administration: 7-10 days Pelvic infection: 500 mg intravenously once daily for 1-2 days, followed by oral administration of 250 mg once daily for 5-6 days. Total duration of intravenous and oral administration: 7 days

Precautions

This drug is an antibiotic called azithromycin, used to treat certain bacterial infections. When using this drug, there may be allergic reactions, so if symptoms such as rash, difficulty breathing, or swelling of the face or lips occur, discontinue use immediately and consult a doctor. Additionally, this drug can affect the balance of intestinal bacteria and may cause diarrhea or severe colitis, so if symptoms of diarrhea are severe or there is blood mixed in, quickly visit a hospital. Patients with severely reduced kidney or liver function may have increased levels of this drug, thereby increasing the risk of side effects; these patients need special attention. During administration, gastrointestinal disturbances, nausea, vomiting, abdominal pain, and skin rashes may occur, and rarely, abnormalities in liver function or decreased blood cell counts and muscle-related symptoms may also arise, so inform a doctor if any unusual symptoms occur. This drug should be diluted and slowly infused when administered intravenously, and care should be taken as pain or inflammation may occur at the injection site. It can affect heart rate, so patients with heart disease or those taking certain medications should consult a doctor, especially those at risk of QT interval prolongation. During pregnancy, the safety for the fetus is not fully established, so it should only be used as necessary under a doctor’s judgment. If breastfeeding, as the drug may pass into breast milk, consult a doctor about weaning or discontinuing the drug. The safety and effectiveness of this drug for intravenous use in children under 16 years old have not been established, thus caution is needed. Elderly patients may have a higher risk of arrhythmias, requiring special attention during administration. This drug may interact with other medications, so inform a doctor or pharmacist about any other medications being taken. Lastly, this drug is not effective against viral infections, and it must be taken exactly as directed by a doctor during the treatment period. Even if symptoms improve during treatment, do not stop taking the medication and continue for the prescribed duration.

Side effects

Angioedema, anaphylaxis, acute generalized exanthematous pustulosis, Stevens-Johnson syndrome, toxic epidermal necrolysis, drug reactions accompanied by eosinophilia and systemic symptoms, diarrhea, colitis, abdominal pain, nausea, vomiting, rashes, injection site pain, injection site inflammation, vulvovaginitis, loss of appetite, pruritus, gastritis, dizziness, dyspnea, dyspepsia, bloating, mucositis, oral candidiasis, gastroenteritis, headache, insomnia, bronchospasm, dysgeusia, hepatitis, liver dysfunction, jaundice, leukopenia, agranulocytosis, thrombocytopenia, rhabdomyolysis, myalgia, feelings of exhaustion, elevated CK, increased myoglobin in blood and urine, arthralgia, edema, urticaria, ventricular tachycardia, arrhythmia, hypotension, QT interval prolongation, torsades de pointes, pseudomembranous colitis, pancreatitis, oral candidiasis, pyloric stenosis, tongue discoloration, weakness, paresthesia, sensory loss, fatigue, myasthenia, interstitial nephritis, acute renal failure, candidiasis, hypoprothrombinemia, liver necrosis, liver failure, seizures, dizziness, surface, hyperactivity, nervous hyperreactivity, anxiety, agitation, syncope, aggressive reactions, hearing loss, auditory impairment, hearing impairment, tinnitus, dysgeusia, hyposmia, ageusia, anosmia, elevated liver enzymes, anemia, nausea, decreased therapeutic response, hypokalemia, leukopenia

Not everyone experiences these, and they can vary from person to person.

Storage

This drug should be stored in a sealed container to prevent air or moisture from entering, and it is advisable to keep it at room temperature, below 25 degrees Celsius. Storing it this way can help maintain its effectiveness for a longer time.

Appearance and packaging

Appearance

A vial filled with white to off-white powder

Package unit

1.107g/vial X 10 vials

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.