Medication info
Kytril Tablets 1 mg (Granisetron Hydrochloride)

Kytril Tablets 1 mg (Granisetron Hydrochloride)

Prescription medicationTabletOral
Ingredient · strength
Granisetron Hydrochloride›1.1mg / 1 tablet
Manufacturer / importer
ZP Therapeutics Korea Co., Ltd.
Appearance
White to almost white film-coated tablet, capsule-shaped with convex surfaces on both sides
Packaging
10 tablets (10 tablets in PTP packaging × 1)
Approval status
Active

MFDS item code 200108800 · Notified 2001.02.09 · Insurance code 057200070

Summary

Main use
Prevention of nausea and vomiting caused by chemotherapy and radiation therapy
Who takes it
Adults
Adult dose
1. Adults 1) Chemotherapy During chemotherapy (up to one week after chemotherapy), administer granisetron 1 mg twice daily or 2 mg once daily. The initial dose should be administered within 1 hour before starting chemotherapy, and the maximum daily dose should not exceed 9 mg. 2) Radiotherapy During radiotherapy, administer 2 mg of this medicine once daily. The initial dose should be administered within 1 hour before starting radiotherapy, and the maximum daily dose should not exceed 9 mg. 2. Older adults No special dosage or administration adjustments are necessary. 3. Patients with renal or hepatic impairment No special dosage or administration adjustments are necessary.

Ingredients

Importer
ZP Therapeutics Korea Co., Ltd.

Efficacy & effects

Prevention of nausea and vomiting caused by chemotherapy and radiation therapy

  • Nausea
  • vomiting
View approved original text

This medication is used to relieve symptoms of nausea and vomiting caused by chemotherapy or radiotherapy.

How to take

Adult dose

1. Adults 1) Chemotherapy During chemotherapy (up to one week after chemotherapy), administer granisetron 1 mg twice daily or 2 mg once daily. The initial dose should be administered within 1 hour before starting chemotherapy, and the maximum daily dose should not exceed 9 mg. 2) Radiotherapy During radiotherapy, administer 2 mg of this medicine once daily. The initial dose should be administered within 1 hour before starting radiotherapy, and the maximum daily dose should not exceed 9 mg. 2. Older adults No special dosage or administration adjustments are necessary. 3. Patients with renal or hepatic impairment No special dosage or administration adjustments are necessary.

Precautions

This medication should not be used by patients who have had an allergic reaction to this medication or any of its other ingredients. This medication contains lactose, so patients with hereditary conditions that affect lactose digestion should not take it. This medication may slow intestinal motility, so patients with symptoms of intestinal obstruction should be monitored closely after taking it. Patients with heart rhythm problems or those with irregular electrocardiograms should exercise caution when taking this medication. Common side effects may include headache or constipation, and some patients may experience allergic reactions or skin rashes. This medication may have a temporary effect on liver function but is generally regarded as safe. Care should be taken when combined with other serotonergic medications, as changes in mental state or neurological symptoms may occur. While there is insufficient information on the effects of this medication on driving or operating machinery, caution is advised as drowsiness may occur. This medication may cause allergic reactions in patients who are hypersensitive to similar components of other 5-HT3 antagonists. Pregnant women should avoid using this medication except in special cases and breastfeeding should be stopped during the treatment period. There is insufficient safety data for children under 12 years of age, so caution is necessary. Elderly individuals may have an increased risk of adverse reactions, so extra caution is warranted during use. In case of overdose, there are no specific antidotes, and symptomatic treatment should be received. Serious side effects are rarely reported, even when taken at doses significantly higher than recommended. Keep out of reach of children, and avoid transferring the medication to another container to maintain quality and safety.

Side effects

  • Hypersensitivity
  • anaphylaxis
  • urticaria
  • headache
  • serotonin syndrome
  • QT prolongation
  • constipation
  • elevated liver enzymes
  • rash
  • diarrhea
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  • nausea
  • vomiting
  • fever
  • hiccups

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent air or moisture from entering. It is best to store it at room temperature which is not too hot or cold.

Appearance and packaging

Appearance

White to almost white film-coated tablet, capsule-shaped with convex surfaces on both sides

Package unit

10 tablets (10 tablets in PTP packaging × 1)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.