Seretide 125 Evohaler

Adult dosage

Adults and children aged 12 and older may receive Salmeterol 25 μg + Fluticasone Propionate 50 μg, 125 μg, or 250 μg via metered-dose inhalation twice daily, with 2 puffs each time.

Children's dosage

There is no useful data on the use of this medication in children under 12.

This medication has a bronchodilatory effect in patients with asthma or chronic obstructive pulmonary disease. However, it should not be used during acute asthma attacks or life-threatening conditions. For rapid symptom relief, a fast-acting inhaler should be used, and this medication is intended for long-term management of symptoms. It should not be administered to patients who are allergic to it, have cardiac arrhythmias, untreated respiratory infections, or severe bronchiectasis. Caution is advised for patients with cardiovascular disease, diabetes, hyperthyroidism, convulsive disorders, pulmonary tuberculosis, and hypokalemia. Rarely, side effects such as palpitations, headache, nausea, vomiting, muscle pain, rash, and oral candidiasis may occur. It is advisable to rinse the mouth after inhalation to prevent oral infections. Immediate medical assessment is necessary if asthma symptoms worsen or the use of a rescue inhaler increases. During pregnancy, it should only be used when the therapeutic benefits outweigh the risks to the fetus, and caution should also be taken during breastfeeding considering the risk to the newborn. Safety in children under 12 has not been established, and system-wide side effects such as growth delay may occur with high-dose long-term use. Elderly patients should also be monitored for cardiovascular adverse effects during administration. In case of overdose, symptoms such as cardiac arrhythmias, hypokalemia, headache, and insomnia may occur, so medical personnel should be notified immediately. It is crucial to use the inhaler correctly and clean it after use, rinsing the mouth to prevent infections. Store the medication in a cool place out of reach of children, and protect it from direct sunlight or high temperatures.

Serious side effects

Hives, angioedema, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe allergic reactions, severe rash with high fever, blisters, skin peeling, pain in the oral/ocular mucosa, severe skin abnormalities, difficulty breathing, asthma attacks, respiratory abnormalities accompanying cough and fever, respiratory problems, yellowing of the skin or eyes (jaundice), profound lethargy, liver abnormalities (jaundice),

Mild side effects

• Nausea
• vomiting
• diarrhea
• abdominal pain
• headache
• tremors
• awareness of palpitations
• tachycardia
• atrial fibrillation
• nonspecific chest pain

This medication should be stored in a sealed container to prevent exposure to light and air, avoiding direct sunlight and keeping it at room temperature. Therefore, to maintain the medication’s effectiveness and safety, it is best to store it in a dry and cool place.

Appearance

A pressurized metered-dose aerosol containing a white to off-white suspension in a metal canister with a dose counter.

Package unit

120 doses/container