Hanmi Clarithromycin Tablets 500 mg

Adult dose

Adults: The usual dose of clarithromycin is 250mg (potency) twice daily. For severe infections, administer 500mg (potency) twice daily. The usual duration of treatment is 7～14 days. In patients with renal impairment and a creatinine clearance of 30mL/min or less, the dose should be reduced by half. That is, administer 250mg (potency) once daily, or, for severe infections, 250mg (potency) twice daily. Do not administer for more than 14 days to these patients. Mycobacterial infections: Administer 500mg (potency) of this medicine twice daily. In this case, it should be administered in combination with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer 500mg (potency) of this medicine three times daily for 14 days in combination with omeprazole 40mg once daily, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) three times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28).

Child dose

Children aged 12 years and older: same as adults For children under 12 years, use clarithromycin dry syrup.

This drug should not be used in certain patients. For example, it should not be administered to those who are allergic to its components, or to patients who have had hypersensitivity to certain antibiotics. Furthermore, it should not be used in patients with irregular heartbeats or severely impaired liver and kidney function, pregnant or breastfeeding women, and patients taking certain medications. This drug should be used cautiously in elderly patients with weakened liver and kidney function or heart disease, and care must be taken regarding drug interactions if taken with other antibiotics. During the use of this medication, allergic reactions or gastrointestinal disturbances, skin rashes, liver function abnormalities, kidney problems, or neurological symptoms may occur; if symptoms arise, consult a doctor or pharmacist immediately. It is important to take antibiotics only for the prescribed duration according to the doctor’s directions to prevent the development of resistant bacteria. In particular, this medication has many drug interactions, so if you are taking other medications, you must inform your healthcare provider; severe side effects can occur when combined with certain drugs, so caution is required. Pregnant or breastfeeding women should avoid this medication, and if it is absolutely necessary to use it, breastfeeding should be stopped after consulting a healthcare professional. Care should also be taken when administering this drug to children or elderly patients, especially since dosage adjustments may be required for elderly patients with reduced kidney function. Overdosage may cause gastrointestinal disturbances or psychiatric symptoms, so adherence to the prescribed usage and dosage is strictly required. This medication should be stored at room temperature away from direct sunlight and should not be refrigerated.

Shock, anaphylactic symptoms, shortness of breath, seizures, flushing, rash, itching, hives, skin redness, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, discomfort, flatulence, diarrhea, oral mucosal erosion, upper abdominal pain, thirst, teeth discoloration, pancreatitis, increased amylase, dysgeusia, decreased appetite, constipation, stool discoloration, pseudomembranous colitis, hemorrhagic colitis, fever, cough, eosinophilia, eosinophilic pulmonary infiltration, interstitial pneumonia, chronic bronchitis, acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, taste loss, olfactory loss, anxiety, insomnia, nightmares, tinnitus, confusion, orientation disturbance, hallucinations, psychosis, depersonalization, seizures, tremors, numbness, behavioral changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash with eosinophilia and systemic symptoms, jaundice, hepatocellular hepatitis, cholestatic hepatitis, elevation of liver enzymes, liver dysfunction, liver failure, fulminant hepatitis, increased AST, increased ALT, increased γ-GTP, increased LDH, increased ALP, elevated total bilirubin, increased serum creatinine, elevated BUN, interstitial nephritis, kidney failure, rhabdomyolysis, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, malaise, headache, ageusia, hearing loss, paresthesia, arthralgia, myalgia, olfactory disturbance, tinnitus, auditory impairment, hypoglycemia, purpuric rash, acute generalized exanthematous pustulosis, muscle cramps, musculoskeletal stiffness, myopathy, elevated serum creatinine, increased blood urea, nephritis, venous thrombophlebitis at injection site, injection site pain, injection site inflammation, fever, weakness, chest pain, chills, fatigue, abnormal albumin-globulin ratio, increased serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased international normalized ratio, prolonged prothrombin time, abnormal urine color

This drug is sensitive to light, so it should be stored in a lightproof, tightly sealed container. It is recommended to keep it at room temperature between 1 degree Celsius and 30 degrees Celsius. Storing it this way helps maintain the medication's effectiveness for a longer time.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle