Ofloksasin Tablets

Adult dosage

○ The usual adult dose is 300～600 mg of ofloxacin per day, divided into 2～3 doses. ○ For Hansen's disease, the dose of this medicine is 400～600 mg per day, divided into 2～3 doses. In principle, use in combination with other anti-leprosy drugs. Adjust the dose as appropriate according to age and symptoms.

This medication can cause serious tendon problems such as tendonitis and tendon rupture; if these symptoms occur, use should be discontinued immediately. It may affect peripheral neuropathy or the central nervous system, so caution is necessary if sensory abnormalities or neurological symptoms occur. It should not be used in patients with myasthenia gravis due to the risk of worsening symptoms, and if a patient with myasthenia gravis is taking it, watch out for symptom exacerbation. Elderly patients, those with renal disorders, and patients taking steroids are at an increased risk of tendon rupture, so combining it with steroids should be avoided. This medication can cause seizures or convulsions, so patients with epilepsy or central nervous system disorders should be especially cautious. Pregnant women, breastfeeding mothers, and children and adolescents in growth should not use this medication. Serious hypersensitivity reactions, such as allergic reactions or anaphylaxis, may rarely occur; if symptoms such as rash or difficulty breathing occur, immediate treatment is necessary. It can affect liver and kidney functions, so routine blood tests and function tests are needed during prolonged use. Avoid exposure to sunlight or UV radiation while taking this medication, and discontinue use if photosensitivity reactions occur. Diabetic patients who need blood sugar control should carefully monitor for symptoms of hypoglycemia or hyperglycemia, and should be cautious if used in combination with antihypertensives or anticoagulants according to a physician's instructions. Be cautious of neurological adverse reactions such as dizziness or drowsiness while driving or operating machinery or during activities that require attention. This medication may have reduced absorption when taken with certain antacids or drugs containing iron or calcium, so the timing of doses should be adjusted. Store in a tightly sealed container away from children and do not transfer to another container for safety.

Tendinitis, tendon rupture, peripheral neuropathy, central nervous system effects, exacerbation of myasthenia gravis, anaphylactic shock, anaphylactic reaction, rash, itching, redness, swelling, fever, warmth, vesicles, erythema, photosensitivity reaction, hematuria, acute kidney failure, kidney stones, interstitial nephritis, elevated BUN, elevated serum creatinine, jaundice, liver failure, elevated AST/ALT, elevated ALP, elevated γ-GTP, elevated total bilirubin, cholestatic jaundice, fulminant hepatitis, pseudomembranous colitis, abdominal pain, frequent diarrhea, nausea, vomiting, gastrointestinal discomfort, diarrhea, cirrhosis, loss of appetite, abdominal pain, dyspepsia, chest pain, thirst, taste alteration, stomatitis, glossitis, abdominal bloating, constipation, dysphagia, gastrointestinal bleeding, oral mucosal pain, intestinal perforation, anemia, leukopenia, decreased hemoglobin, decreased hematocrit, thrombocytopenia, eosinophilia, agranulocytosis, thrombotic thrombocytopenic purpura, petechiae, prolonged prothrombin time, reversible bone marrow suppression, lymphopenia, neutropenia, increased ESR, insomnia, dizziness, headache, convulsions, tremors, numbness, peripheral nerve disorders, visual disturbances, auditory disturbances, hallucinations, drowsiness, neurogenic irritability, sleep disorders, confusion, anxiety, depression, restlessness, psychosis, seizures, nightmares, paranoia, disorientation, attention deficit, memory impairment, delirium, suicidal ideation, suicide, perceptual disturbances, reversible olfactory and equilibrium disorders, ataxia, aphasia, heaviness in the head, skin-mucous membrane syndrome, toxic epidermal necrolysis, arthralgia, myalgia, muscle weakness, myositis, malaise, elevated CPK, increased myoglobin in blood and urine, rhabdomyolysis, pharyngitis, dyspnea, bronchospasm, allergic pneumonia, nosebleeds, stridor, fever, cough, abnormal chest X-ray, eosinophilia, interstitial pneumonia, cerebral thrombosis, pulmonary edema, tachycardia, hypertension, hypotension, palpitations, vasodilation, circulatory collapse, prolonged QT interval, ventricular tachycardia, dysuria, frequent urination, urinary retention, anuria, polyuria, hematuria, storage urine, pyuria, diabetes, proteinuria, alkaline urine, vaginitis, vaginal candidiasis, increased vaginal discharge, itching of the female external genitalia, menstrual irregularities, uterine cramps, female genital rash, pain, irritation, burning sensation, hypoglycemic symptoms, limb pain, fatigue, fever, drowsiness, nausea, facial flushing, facial swelling, numbness, speech inaccuracies, loss of directional sense

This medication should be stored in a tightly sealed container that allows for good air circulation, at room temperature, between 1 degree and 30 degrees Celsius. This helps to maintain the drug's effectiveness and prevent its degradation.

Appearance

White round film-coated tablets

Package unit

30 tablets/bottle, 500 tablets/bottle