Clasin Tablets (Clarithromycin)

Adult dose

Adults: The usual dose of clarithromycin is 250 mg (potency) per dose twice daily. For severe infections, administer 500 mg (potency) per dose twice daily. The usual duration of treatment is 7–14 days. In patients with renal impairment and a creatinine clearance of 30 mL/min or less, the dose should be reduced by half: 250 mg (potency) once daily, or, for severe infections, 250 mg (potency) per dose twice daily. Do not administer to these patients for more than 14 days. Mycobacterial infections: Administer 500 mg (potency) of this medicine per dose twice daily. In this case, it should be administered in combination with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer 500 mg (potency) of this medicine 3 times daily with omeprazole 40 mg once daily for 14 days, followed by omeprazole 40 mg once daily for 14 consecutive days. That is, administer clarithromycin 500 mg (potency) per dose 3 times daily for 14 days (days 1–14), and omeprazole 40 mg once daily for 28 days (days 1–28).

Child dose

Children aged 12 years and older: Same as adults Children younger than 12 years: Use clarithromycin dry syrup.

This medication should not be administered to certain patients. For instance, patients allergic to the excipients or ingredients in this medication or who have had hypersensitivity to similar classes of antibiotics may face risks. Additionally, it is safer not to administer to patients with severe heart disease, liver dysfunction, or renal impairment, as well as to pregnant or nursing women. This medication may interact with other drugs, so it is essential to consult with a doctor or pharmacist if currently taking other medications. Special caution is needed when taken in conjunction with drugs that may affect heart function or liver function. When using this drug, careful observation for allergic reactions or serious side effects is necessary. If abnormal symptoms such as itching, rash, difficulty breathing, severe abdominal pain, or diarrhea occur, discontinue use immediately and consult a healthcare professional. Patients with weakened liver or kidney function may need dosage adjustments, and elderly patients also require careful monitoring while receiving this medication. Prolonged or repeated use may lead to the emergence of resistant bacteria, so it is crucial to adhere to the prescribed duration and dosage as directed by a physician. It is unsafe to use this drug during pregnancy or breastfeeding, and consultation with a healthcare provider is necessary if required. This medication may cause dizziness or confusion while driving or operating machinery, so caution is advised when engaging in such activities. In case of overdose, gastrointestinal disturbances or central nervous system abnormalities may occur, so it is essential to adhere to the prescribed dosage. Store this medication in a container that blocks light and allows for air circulation. It is recommended to keep it at room temperature between 15 and 30 degrees Celsius.

Shock, anaphylactic symptoms, dyspnea, convulsions, flushing, rash, itching, urticaria, skin flushing, angioedema, joint swelling, drug rash, abdominal bloating, nausea, vomiting, dyspepsia, abdominal pain, malaise, bloating, diarrhea, oral mucosal ulceration, upper abdominal pain, thirst, transient discoloration of teeth, pancreatitis, increased amylase, dysgeusia, anorexia, constipation, discoloration of stool, pseudomembranous colitis, hemorrhagic colitis, fever, cough, dyspnea, abnormal chest X-ray, eosinophilia, eosinophilic lung infiltration, interstitial pneumonia, chronic bronchitis, acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, convulsions, tremors, numbness, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash, jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzymes, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, elevated serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, malaise, headache, dysgeusia, hearing loss, paresthesia, arthralgia, myalgia, olfactory disturbance, hypoglycemia, tinnitus, hearing loss, purpuric rash, acute generalized exanthematous pustulosis, muscle cramps, musculoskeletal rigidity, myopathy, elevated serum creatinine, elevated blood urea, renal failure, nephritis, venous inflammation at the injection site, pain at the injection site, inflammation at the injection site, fever, asthenia, chest pain, chills, fatigue, abnormal albumin-globulin ratio, increased serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased INR, prolonged prothrombin time, abnormal urine color, asthma, epistaxis, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, distention, tongue discoloration, tooth discoloration, hyperhidrosis, vesicular dermatitis, papular rash, acne, Henoch-Schonlein purpura

This medication should be stored in a container that blocks light and allows for proper air circulation. It should be kept at room temperature between 15 and 30 degrees Celsius.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle, 200 tablets/bottle