Nexium Tablets 20 mg (Esomeprazole Magnesium)

Adult dosage

This medication should be swallowed with liquids such as water and should not be chewed or crushed. Patients who have difficulty swallowing tablets may dissolve this medication in half a cup of non-carbonated water. Other beverages may dissolve the enteric coating and should not be used. The dissolved medication should be swallowed without chewing immediately or within 30 minutes, and the cup should be rinsed with half a cup of non-carbonated water and consumed. Patients who cannot swallow the tablet

Children's dosage

Adolescents aged 12 and above - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks. - Symptomatic treatment without esophagitis: 20 mg once daily. Children under 12 years: No dosing experience available.

This drug should not be used in patients with specific allergic reactions or hypersensitivity. For example, it should not be administered to patients allergic to this drug, any of its components, or benzimidazole drugs. Care should be taken when administering it in combination with certain antibiotics (penicillin group, macrolide group) used for Helicobacter pylori eradication, especially in patients with hypersensitivity reactions. It may also pose risks when used in combination with certain cardiac medications or antiviral agents, so consultation with healthcare professionals is essential. This medication is not recommended for use by nursing women. Various adverse reactions may occur after administration, including headache, abdominal pain, diarrhea, skin rash, myalgia, and hypomagnesemia. Rarely, severe allergic reactions, liver dysfunction, and severe skin reactions may occur, thus symptoms should be immediately reported to healthcare professionals. Long-term use requires regular testing and monitoring. Caution is advised especially in patients taking it for more than one year as hypomagnesemia and fracture risk may increase. This medication can suppress gastric acid secretion, thereby increasing the risk of bacterial overgrowth in the gastrointestinal tract; if infection symptoms persist, consultation with a physician is necessary. Due to many drug interactions, it is imperative to inform healthcare professionals about currently taken medications, particularly when taking anticoagulants, antiviral agents, certain antibiotics, and antiepileptic drugs. Safety data regarding use during pregnancy is limited, hence it should be used cautiously in pregnant women. There is no specific antidote for dosage overdose, therefore appropriate treatment based on symptoms must be received, and it is important to keep it out of reach of children.

Serious side effects

Urticaria, angioedema, anaphylactic reaction, shock, severe hypomagnesemia, mental confusion, bronchospasm, pancreatitis, jaundice, liver failure, encephalopathy, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell syndrome), acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), muscle weakness, interstitial nephritis, Clostridium difficile-associated diarrhea.

Mild side effects

Headache, dizziness, altered sensation, drowsiness, taste disturbance, blurred vision, bronchospasm, abdominal pain, constipation, diarrhea, abdominal bloating, nausea, vomiting, dry mouth, stomatitis, gastrointestinal candidiasis, increased liver enzymes, hepatitis, dermatitis, itching, rash, hair loss, photosensitivity, fractures, arthralgia, myalgia, interstitial nephritis, gynecomastia, weakness, increased sweating, Clostridium difficile-associated diarrhea, allergic reactions, back pain, chest pain, facial swelling.

This medication may be sensitive to air and moisture, thus it should be stored in a tightly sealed container. Additionally, it is best to store the medication at room temperature that is not excessively hot or cold.

Appearance

Light pink rectangular film-coated tablet

Package unit

14 tablets (7 tablets/PTP x 2)