Clarithromycin Dry Syrup 250mg/5mL (Clarithromycin)

Child dose

The usual pediatric dose is 7.5mg per Kg of body weight every 12 hours (15mg/Kg/day). The usual duration of treatment is 5～10 days. Since the bioavailability of this medicine is not affected by food, it may be administered with or without food. It may be taken with food or milk. For patients with renal failure whose creatinine clearance is 30mL/min/1.73m2 or less, the dose should be reduced by half. Do not administer to these patients for more than 14 days. ○ Mycobacterial infections Administer 7.5～15mg per Kg of body weight every 12 hours (15～30mg/Kg/day) to children. Continue administration if clinical improvement is observed. Do not exceed 500mg (potency) per dose, twice daily, as clarithromycin (potency). It should be administered concomitantly with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin.

This medication should not be used by patients who are allergic to certain ingredients or who have hypersensitivity to macrolide antibiotics. It should not be administered to patients taking medications that may affect heart rhythm or those with a history of prolonged QT intervals. It is safe not to use this medication in patients with severely impaired liver function and in pregnant or lactating women. This medication should be used with caution in patients with impaired kidney function, the elderly, or those with heart disease, and dosage adjustments may be necessary. This medication can interact with various drugs, so patients taking other medications must consult a doctor or pharmacist. If severe allergic reactions, heart irregularities, severe abdominal pain or diarrhea, skin rashes, or other unusual symptoms occur during use, discontinue use immediately and inform medical personnel. Long-term or high-dose use may cause hearing impairment or tinnitus, so if any unusual symptoms occur, consult medical personnel. This medication contains lactose, so patients with lactose intolerance should exercise caution. It is important to adhere strictly to the prescribed duration and dosage to prevent the development of resistance in infectious bacteria. If this medication must be administered, regular blood tests and assessments of liver and kidney function should be conducted to monitor for side effects. This medication may affect driving or operating machinery, so caution is necessary during use. Children may require appropriate dosage adjustments according to their age, and its use may be restricted for infants under 6 months or children under 12 years.

Shock, anaphylactic symptoms, dyspnea, convulsions, flushing, rash, itching, urticaria, mild skin erythema, angioedema, joint swelling, drug rash, abdominal distension, nausea, vomiting, dyspepsia, abdominal pain, discomfort, flatulence, diarrhea, oral mucosal erosion, upper abdominal pain, thirst, transient tooth discoloration, pancreatitis, increased amylase, taste disturbance, anorexia, constipation, stool discoloration, pseudomembranous colitis, hemorrhagic colitis, abdominal pain, frequent diarrhea, fever, cough, chest X-ray abnormalities, eosinophilia, eosinophilic lung infiltration, interstitial pneumonia, chronic bronchitis, acute exacerbation of acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, convulsions, tremors, numbness, behavioral changes, manic behavior, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, Drug Rash with Eosinophilia and Systemic Symptoms (DRESS), jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzyme levels, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, increased γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, anorexia, dark urine, pruritus, abdominal tenderness, elevated serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de Pointes, lethargy, headache, taste distortion, hearing loss, paresthesia, arthralgia, myalgia, olfactory disturbance, tinnitus, auditory impairment, hypoglycemia, tinnitus, hearing loss, vomiting, nausea, abdominal pain, purpuric rash, acute generalized exanthematous pustulosis (AGEP), angioedema, anaphylactic reaction, vasodilation, bleeding, asthma, epistaxis, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, bloating, acute pancreatitis, tongue discoloration, tooth discoloration, abnormal liver function tests, abnormal albumin/globulin ratio, increased serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased international normalized ratio, prolonged prothrombin time, abnormal urine color, injection site phlebitis, injection site pain, injection site inflammation, fever, weakness, chest pain, chills, fatigue, dyskinesia, non-vertiginous dizziness, drowsiness, tremors, loss of consciousness, muscle cramps, musculoskeletal rigidity, myopathy, elevated blood urea, nephritis, vasodilation, psychotic disorder, confusion state, abnormal dreams, vestibular vertigo, hearing impairment, cardiac arrest, atrial fibrillation, premature contractions, palpitations, ventricular fibrillation, myocardial infarction, cardiovascular death, hypotension, bradyarrhythmia, lactic acidosis, hypokalemia, hypoxemia, changes in mental administration, obsessive behavior

This medication must be stored in a tightly sealed container to prevent air and moisture ingress. It is crucial to maintain a storage temperature between 1 and 30 degrees Celsius at room temperature. Proper storage will help maintain the drug's effectiveness for an extended period.

Appearance

White to off-white granulated powder

Package unit

70 milliliters/bottle