Hyun's Ceftriaxone Sodium Injection 250mg

Adult administration

For adults and children over 12 years of age, administer 1 to 2 g (potency) of ceftriaxone intravenously or intramuscularly once daily. In cases of severe illness or infections caused by moderately sensitive pathogens, the dosage may be increased to 4 g (potency) once daily.

Child administration

In newborns (within 14 days of birth), administer 20 to 50 mg/kg (potency) once daily, without exceeding 50 mg/kg (potency). It is not necessary to distinguish between premature infants and full-term infants for administration.

This medication may be dangerous if mixed or administered simultaneously with solutions or drugs containing calcium, so it must be administered separately. Particularly, it should never be administered to newborns under 28 days old as the combination of calcium and this medication poses a high risk of precipitation. There have been reports of fatal outcomes due to precipitation in the lungs or kidneys of newborns receiving this medication and calcium simultaneously, so great caution is required. Patients with allergies to this medication or its components, especially those who have had hypersensitivity reactions to cephalosporin or penicillin antibiotics, should not be treated with this medication. Additionally, patients with hypersensitivity reactions to local anesthetics such as lidocaine should avoid intramuscular injection of this medication, and this medication containing lidocaine should not be used for intravenous injection. This medication should not be used in newborns suspected of having bilirubin conjugation disorders or in newborns receiving calcium-containing solutions. Extreme caution is needed when administering to patients with a history of allergic reactions to this medication or similar antibiotics, especially in patients with severely impaired kidney function or the elderly, as well as those in poor general condition, requiring dosage adjustments and monitoring. During administration, regular blood tests, liver and kidney function assessments should be conducted to carefully observe for adverse reactions. Various side effects such as diarrhea, rash, headache, dizziness, elevated liver enzymes, blood abnormalities may occur during the administration of this medication, so any symptoms should be immediately reported to medical personnel. Immediate cessation of administration and emergency treatment are necessary if signs of allergic reactions or shock symptoms appear. The safety of this medication during pregnancy has not been fully established, and pregnant or breastfeeding women should use it cautiously after consulting a physician. It is advisable not to use this medication in newborns or premature infants due to the risk of bilirubin encephalopathy. This medication can interact with other drugs, so tell your healthcare provider if you are taking any other medications. Caution should be taken when driving or operating machinery due to possible side effects such as dizziness. Lastly, this medication should be used as soon as possible after preparation, and storage should comply with specified conditions.

Serious side effects

Hives, severe swelling (edema), swelling, chest tightness, difficulty breathing, cold sweat, pallor, hypersensitivity reactions, anaphylaxis, anaphylactic shock symptoms, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, severe skin reactions, difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, bronchospasm, yellowing of the skin or eyes (jaundice), extreme lethargy

Mild side effects

• Eosinophilia
• leukopenia
• thrombocytopenia
• diarrhea
• rash
• increased liver enzymes
• headache
• dizziness
• bronchospasm
• loose stools

This medication should be stored in a sealed container to prevent air and moisture from entering, and it is important to maintain the storage temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the effectiveness of the medication for a long time.

Appearance

A vial containing a white to light yellow powder

Package unit

1 vial