Claroma Tablets 250 mg (Clarithromycin)

Adult dose

Adults: The usual dose of clarithromycin is 250mg (potency) twice daily; for severe infections, administer 500mg (potency) twice daily. The usual treatment duration is 7～14 days. In patients with renal impairment and creatinine clearance of 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or 250mg (potency) twice daily for severe infections. Do not administer for more than 14 days to these patients. Mycobacterial infections: Administer 500mg (potency) of this medicine twice daily. In this case, it should be administered in combination with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer 500mg (potency) of this medicine 3 times daily for 14 days with omeprazole 40mg once daily, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) per dose 3 times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28).

Child dose

Children aged 12 years and older: Same as adults Children under 12 years: Use clarithromycin dry syrup.

This medication should not be used in patients who are allergic to certain components or who have had prior allergic reactions to this drug or similar antibiotics. Additionally, it should not be taken with certain drugs that may affect heart rhythm due to the risk of arrhythmias and other heart issues. It should also be avoided in patients with severely impaired liver or kidney function, as well as in pregnant or breastfeeding women. This drug can rarely cause serious allergic reactions, gastrointestinal disturbances, liver dysfunction, kidney problems, skin rashes, central nervous system disorders, etc. Therefore, if unusual symptoms occur during use, immediate consultation with a doctor is required. To prevent the development of antibiotic-resistant bacteria, it is important to administer this drug only for the necessary duration and not to stop it arbitrarily. There are many interactions with other medications, so it is essential to inform healthcare providers of any currently taken medications, especially for patients with specific heart diseases, the elderly, or those with compromised liver or kidney functions. Pregnant or breastfeeding women should avoid this drug and, if necessary, discontinue breastfeeding. Use in children is restricted; safety in children under 12 years old and infants under 6 months has not been established. In case of overdose, gastrointestinal disturbances or central nervous system disorders may occur, thus the dosage should be strictly followed, and immediate medical attention sought in case of overdose.

Shock, anaphylactic symptoms, respiratory distress, seizures, erythema, rash, itching, hives, skin erythema, angioedema, joint swelling, drug rash, abdominal bloating, nausea, vomiting, indigestion, abdominal pain, discomfort, gas retention, diarrhea, oral mucosal erosion, epigastric pain, thirst, transient tooth discoloration, pancreatitis, increased amylase, dysgeusia, loss of appetite, constipation, colored stools, membranous colitis, hemorrhagic colitis, fever, cough, abnormal chest X-ray, eosinophilia, eosinophilic pulmonary infiltrates, interstitial pneumonia, chronic bronchitis, exacerbation of acute maxillary sinusitis, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, taste loss, smell loss, anxiety, insomnia, nightmares, tinnitus, disorientation, impaired orientation, hallucinations, psychosis, depersonalization, tremors, numbness, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash (DRESS), jaundice, hepatocellular hepatitis, cholestatic hepatitis, elevated liver enzymes, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, elevated serum creatinine, elevated BUN, interstitial nephritis, renal failure, rhabdomyolysis, glossitis, stomatitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, fatigue, headache, taste distortion, hearing loss, paresthesia, arthralgia, myalgia, olfactory dysfunction, hypoglycemia, tinnitus, hearing disorders, vasodilation, angioedema, vesicular dermatitis, papulovesicular rash, acne, Henoch-Schonlein purpura, acute generalized eruptive pustulosis, muscle cramps, musculoskeletal stiffness, myopathy, elevated blood urea nitrogen, intravenous injection site thrombophlebitis, injection site pain, injection site inflammation, fever, asthenia, chest pain, chills, fatigue, abnormal albumin-globulin ratio, elevated serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased INR, prolonged prothrombin time, abnormal urine color, asthma, epistaxis, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, bloating, tongue discoloration, tooth discoloration, cardiac arrest, atrial fibrillation, ectopic beats, palpitations, myocardial infarction, cardiovascular death, changes in mental status, compulsive behavior, hypokalemia, hypoxemia

This medication should be stored in a tightly closed container that blocks light, at room temperature between 1°C and 30°C. Storing it this way helps maintain its effectiveness over time.

Appearance

Yellow oval film-coated tablet

Package unit

30 tablets, 100 tablets