Ascontin Sustained Release Tablets for Children (Aminophylline Hydrate)

Adult dose

(Extended-release tablet) 225 mg Adults: The initial dose is 225 mg of aminophylline hydrate twice daily (morning and evening) by oral administration. Depending on symptoms, the dose may be increased to 450 mg per dose twice daily (morning and evening). Do not chew or crush the tablets. Adjust the dose as appropriate according to symptoms.

Child dose

(Extended-release tablet) 100 mg Children: Administer the following doses of aminophylline hydrate orally. Do not chew or crush the tablets. 8 ∼ 12 years: 100 ∼ 200 mg per dose twice daily (morning and evening) 4 ∼ 7 years: 100 mg per dose twice daily (morning and evening) Adjust the dose as appropriate according to age and symptoms.

The dosage of this medication should be adjusted appropriately while periodically checking blood concentration. If the blood concentration is too high, serious side effects such as severe convulsions or arrhythmia may occur. Patients with heart disease should be particularly cautious when using this medication. When using injectable ampoules, it is important to open them carefully as glass fragments may mix in, and more attention should be given when administering to children and the elderly. Patients who have had allergies or hypersensitivity reactions to this medication or similar ingredients, those with gastric or duodenal ulcers, porphyria, acute tachyarrhythmia or myocardial infarction should not use this drug. Specific patient populations, such as those with epilepsy, hyperthyroidism, renal and hepatic impairment, high blood pressure, elderly patients, pregnant or breastfeeding women should use this medication cautiously, and patients with a history of allergies should also be careful. Various side effects such as headaches, insomnia, anxiety, dizziness, nausea, vomiting, loss of appetite, palpitations, and arrhythmia can occur while using this medication. Rarely, rhabdomyolysis or hepatic dysfunction may occur, so the condition should be carefully monitored. Smoking, alcohol consumption, and interactions with other medications may change the efficacy of this medication, so if you are taking other medications, be sure to inform your healthcare provider and adjust dosages according to their directives. Women who are pregnant or breastfeeding should only use this medication if deemed necessary by a healthcare provider, as it may affect the fetus or newborn. It is advisable not to administer this medication to infants under 6 months, and children with a history of epilepsy or seizures should use it cautiously as seizures may be triggered. Elderly patients may have increased drug concentration due to decreased liver function, so dosages should be adjusted and monitored closely. Rapid administration of this medication may result in side effects such as a feeling of warmth, arrhythmias, hyperventilation, shock, so dilution and administration should be done slowly for safety. In case of overdose, serious symptoms such as nausea, vomiting, convulsions, and cardiac arrhythmias may occur, so immediate medical attention is required. The risk of adverse effects may increase depending on the blood concentration of this medication, so regular testing is necessary, and any abnormal symptoms should be reported to healthcare providers immediately.

• Convulsions
• supraventricular tachycardia
• shock
• headache
• insomnia
• central nervous system stimulation
• anxiety
• dizziness
• tinnitus
• tremors

This medication is sensitive to light, so it should be stored in a container that blocks light. Additionally, it is important to store it at room temperature between 1 to 30 degrees Celsius to maintain its effectiveness.

Appearance

The tablet is round and light orange in color.

Package unit

500 tablets per bottle