Nofaxin Tablets (Levofloxacin Hemihydrate)

Adult dose

Generally, for adults, levofloxacin is administered orally at a dose of 100 mg once 2 to 3 times a day. For patients with severe or insufficient efficacy, it is administered at a dose of 200 mg once 3 times a day. Dosage may be adjusted according to age and symptoms.

This drug, being a fluoroquinolone antibiotic, may cause tendon-related issues such as tendonitis or tendon rupture, so caution is required. Additionally, symptoms of peripheral neuropathy, central nervous system abnormalities, and muscle weakness may occur, hence it should not be administered to patients with myasthenia gravis. If sudden pain, inflammation, or tendon rupture symptoms occur during the use of this drug, it should be discontinued immediately, and medical consultation should be sought. Elderly patients, patients with decreased renal function, and those undergoing immunosuppressive therapy are at higher risk for these side effects and require caution. This drug may also increase the risk of seizures; therefore, patients with a history of seizures or central nervous system diseases should be administered this treatment cautiously. It should not be used in pregnant women, children in growth periods, patients with epilepsy, and those allergic to this drug or similar medications. This drug may have reduced efficacy when taken together with certain antacids or medications containing iron or calcium, so a time gap between doses should be ensured. Diabetic patients taking blood sugar control medication must closely monitor blood sugar fluctuations, and there is a risk of bleeding, hence blood tests are needed when used with anticoagulants. During the use of this drug, care should be taken to avoid excessive sun exposure, and if skin rashes or photosensitivity reactions occur, usage must be suspended immediately. Be cautious of dizziness or drowsiness when driving or operating machinery. In case of overdose, central nervous system symptoms and cardiac arrhythmias may occur, so immediate medical attention is necessary, and this drug cannot be removed by dialysis.

Serious side effects

Hives, severe swelling (edema), tightness in the chest, difficulty breathing, cold sweat, pallor, severe rashes with high fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory distress with cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, lightning headache, seizures, confusion, visual disturbances, paralysis, urine.

Mild side effects

• Nausea
• diarrhea
• vaginitis
• insomnia
• abdominal pain
• bloating
• itching
• dizziness
• rash
• indigestion

This medication should be stored in a tightly closed container to prevent air entry and kept at a temperature between 1°C to 30°C at room temperature. Storing it this way will help maintain the drug's effectiveness.

Appearance

White to off-white film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle