Apenac Tablet (Aseclofenac)

Adult dose

As Aseclofenac, take 100 mg twice daily every 12 hours. Do not chew or crush the tablet, take it as is. Adjust dosage as appropriate according to symptoms. To minimize cardiovascular adverse reactions, administer the lowest effective dose for the shortest duration.

This medication may increase the risk of gastrointestinal bleeding in individuals who regularly consume more than three glasses of alcohol per day, so it is essential to consult a doctor or pharmacist. This medication may increase the risk of cardiovascular diseases; thus, patients with risk factors such as hypertension, diabetes, or smoking should take it cautiously, using the lowest effective dose for the shortest duration. This medication can cause gastrointestinal adverse reactions such as gastrointestinal bleeding, ulcers, and perforation, especially in elderly patients or those with a history of gastrointestinal diseases. Patients with active peptic ulcers or bleeding, those allergic to this medication or similar medications, those sensitive to asthma or aspirin, and patients with severe heart failure or severe kidney or liver dysfunction should not take this medication. Patients with renal impairment, heart failure, elderly patients, and those with hypertension should have careful evaluation and periodic monitoring by a physician when taking this medication. This medication may cause side effects such as dizziness, gastrointestinal discomfort, abnormal liver enzyme levels, skin rash, and in severe cases, blood abnormalities, anaphylaxis, hepatitis, and kidney failure may occur. Regular blood pressure, liver function, renal function, and blood tests are essential while taking this medication, and any abnormal symptoms should be reported to a healthcare professional immediately. This medication should not be used in late pregnancy as it may harm the fetus, and should be used with caution at the lowest dose and shortest duration during early and mid-pregnancy. Lactating women should consider discontinuing breastfeeding or the medication as it may be excreted into breast milk. This medication may interact with other medications; therefore, it is crucial to consult a physician if taken with digoxin, anticoagulants, diabetes medications, diuretics, lithium, methotrexate, etc. Dizziness or drowsiness may occur, so caution is advised when driving or operating dangerous machinery. This medication has not been established for safety and efficacy in children, so it is not recommended for use. In case of overdose, gastrointestinal irritation, hypotension, respiratory depression, and convulsions may occur, requiring immediate medical attention. This medication should be stored out of reach of children and should not be transferred to another container.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, severe skin reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, respiratory issues, jaundice (yellowing of the skin or eyes), extreme lethargy, liver abnormalities (jaundice), sudden

Mild side effects

• Dizziness
• abnormal liver enzyme levels
• itching
• rash
• anemia
• hyperkalemia
• depression
• unusual dreams
• insomnia
• visual disturbances

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. The storage temperature should be kept at room temperature between 1°C and 30°C.

Appearance

White round film-coated tablet

Package unit

For domestic use: 30 tablets/bottle, 300 tablets/bottle, 500 tablets/bottle For export: 100 tablets (10 tablets/PTP × 10)