Levofloxacin Tablets (Levofloxacin Hydrate)

Adult dose

Typically, for adults, levofloxacin 100 mg is administered orally 2 to 3 times a day. For patients with severe infections or insufficient efficacy, 200 mg is administered 3 times a day. Adjustments are made based on age and symptoms.

This medication is a fluoroquinolone antibiotic and is used for the treatment of acute bacterial non-sinusitis, acute bacterial exacerbation of chronic bronchitis, uncomplicated urinary tract infections, acute otitis media, and specific bacterial infections. This medication can cause serious side effects such as tendonitis or tendon rupture, peripheral neuropathy, central nervous system adverse reactions, and exacerbation of myasthenia gravis, thus it should be discontinued immediately if any of these symptoms occur. In patients with a history of myasthenia gravis, this drug may exacerbate symptoms and is not administered. Elderly patients, those with impaired kidney function, solid organ transplant recipients, and patients using corticosteroids should be cautious as the risk of tendon rupture is increased, and concomitant use should be avoided if possible. This medication has neuromuscular blocking effects and can lead to severe adverse reactions in patients with myasthenia gravis. It should not be administered to patients with hypersensitivity to this drug or other drugs in the same class, those with a history of tendonitis or tendon rupture, children and adolescents under 18 years old, pregnant women or women who may become pregnant, nursing mothers, or patients with epilepsy. Patients with severe renal impairment, central nervous system disorders, a history of seizures, those taking certain anti-inflammatory drugs or theophylline, the elderly, diabetic patients, individuals with glucose-6-phosphate dehydrogenase deficiency, or those with a history of aortic aneurysm or heart valve disease should be treated with caution. This medication may cause various adverse effects such as shock, severe allergic reactions, neuropsychiatric disturbances, cardiac arrhythmias, kidney and liver dysfunction, blood disorders, gastrointestinal disturbances, musculoskeletal side effects, severe skin reactions, and respiratory issues, thus it is important to consult a healthcare provider immediately upon the occurrence of symptoms. While taking this medication, strong sunlight or artificial UV exposure should be avoided, and caution should be exercised when driving or operating machinery due to the risk of dizziness or drowsiness. This medication can interact with other drugs, thus patients taking anti-inflammatory drugs, antacids, iron supplements, calcium supplements, anticoagulants, or diabetes medications should inform their healthcare provider and be closely monitored. Pregnant or nursing mothers should not use this medication, and it should not be used in growing children and adolescents. Elderly patients may experience increased drug concentration due to decreased kidney function, necessitating dosage adjustments and caution. In the case of overdose, central nervous system symptoms and cardiac abnormalities may occur, and immediate treatment at a healthcare facility is necessary, as this drug is not removed by dialysis. It is crucial to consult a doctor or pharmacist immediately if any abnormal symptoms or side effects are suspected during treatment with this medication.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor (severe allergic reaction), high fever with severe rash, blisters, skin peeling, pain in oral/ocular mucosa (severe skin adverse reactions), shortness of breath or difficulty in breathing, asthma attacks, respiratory abnormalities accompanied by cough + fever (respiratory problems), yellowing of skin or eyes (jaundice), extreme lethargy (liver dysfunction), sudden onset

Mild side effects

• Nausea
• diarrhea
• vaginitis
• insomnia
• abdominal pain
• bloating
• itching
• dizziness
• rash
• dyspepsia

This medication should be stored in a tightly closed container to prevent exposure to air and moisture, at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness for a longer period.

Appearance

Round tablet of white to off-white color

Package unit

30 tablets/bottle, 100 tablets/bottle