Medication info
Viver tablet 200 mg (Acyclovir)

Viver tablet 200 mg (Acyclovir)

Prescription medicationTablet
Ingredient · strength
Acyclovir›200mg / 1 tablet
Manufacturer / importer
한미약품(주)
Appearance
White hexagonal tablet
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 199902689 · Notified 1999.03.20 · Insurance code 643501110

Summary

Main use
Treatment of herpes simplex and shingles (acute pain) and improvement of chickenpox
Who uses it
Adults · Children
Adult dosage
1. Treatment of herpes simplex virus infections - As acyclovir, 200 mg 5 times a day, at 4-hour intervals for 5 days. - In cases of severe primary infections, treatment extension is possible. - In severely immunocompromised patients or those with gastrointestinal absorption issues, the dose can be increased to 400 mg or switched to intravenous administration. 2. Prevention of herpes simplex infections in patients with normal immune function - 200 mg 4 times a day
Children's dosage
1. Treatment of herpes simplex infections and prevention of herpes simplex infections in patients with impaired immune function - Age 2 and older: Same as adults. - Under 2 years: 1/2 the adult dosage. 2. Chickenpox treatment in children over the age of 2:

Ingredients

Manufacturer
한미약품(주)

Efficacy & effects

Treatment of herpes simplex and shingles (acute pain) and improvement of chickenpox

  • Primary and recurrent genital herpes
  • herpes simplex virus infections of the skin and mucous membranes
  • shingles virus infections
  • acute pain
  • chickenpox
View approved original text

This medication is used for the treatment and prevention of herpes simplex virus infections of the skin and mucous membranes, including primary and recurrent genital herpes. It is also effective in treating shingles virus infections, particularly for alleviating acute pain. However, its efficacy for postherpetic neuralgia has not yet been clearly established. It is also used for the treatment of chickenpox in children over the age of 2, thus aiding in the treatment of viral infections across various age groups. Therefore, this medication is effectively utilized in the treatment and prevention of various viral infections.

Dosage and Administration

Adult dosage

1. Treatment of herpes simplex virus infections - As acyclovir, 200 mg 5 times a day, at 4-hour intervals for 5 days. - In cases of severe primary infections, treatment extension is possible. - In severely immunocompromised patients or those with gastrointestinal absorption issues, the dose can be increased to 400 mg or switched to intravenous administration. 2. Prevention of herpes simplex infections in patients with normal immune function - 200 mg 4 times a day

Children's dosage

1. Treatment of herpes simplex infections and prevention of herpes simplex infections in patients with impaired immune function - Age 2 and older: Same as adults. - Under 2 years: 1/2 the adult dosage. 2. Chickenpox treatment in children over the age of 2:

Precautions

This medication contains lactose; therefore, patients with a genetic disorder that impairs lactose digestion should not take it. Furthermore, patients who have had an allergic reaction to this medication or any of its ingredients should also avoid it. Patients with poor kidney function may experience mental and neurological side effects more easily when using this medication, thus caution is required. Patients with impaired liver function should use this medication carefully as it may worsen liver function. Infants and children should be cautious when using this medication, and elderly patients should also be careful due to higher risks of reducing kidney function and experiencing side effects. While taking this medication, there may be rare occurrences of serious allergic reactions such as anaphylaxis, so if symptoms such as decreased blood pressure, difficulty breathing, or chest tightness appear, the medication should be immediately stopped and medical personnel should be notified. Also, hypersensitivity reactions such as skin rashes, fever, vesicles, and hives may occur, and if such symptoms appear, the medication should be discontinued and appropriate treatment should be sought. Skin-related side effects may include hair loss, severe skin inflammation, and syndromes that cause serious damage to the skin and mucous membranes. Neurological symptoms may include disturbances of consciousness, loss of orientation, decreased concentration, aggression, confusion, hallucinations, convulsions, drowsiness, and insomnia, particularly affecting elderly patients or patients with reduced kidney function. With respect to kidney function issues, symptoms such as renal failure or blood or protein in the urine may manifest. Blood and lymphatic effects may include leukopenia, anemia, bleeding, and lymphadenopathy. Liver function abnormalities such as hepatitis, jaundice, and elevated liver enzymes have been reported, and gastrointestinal issues may include gastritis, vomiting, diarrhea, and abdominal pain, thus the medication should be stopped if symptoms occur. Systemically, symptoms such as fever, muscle weakness, fatigue, and headache may appear, and musculoskeletal symptoms may include joint pain and muscle pain. In the cardiovascular and circulatory systems, arrhythmias, chest pain, and changes in blood pressure may occur, while in the urinary system, difficulties in urination may rarely be seen. This medication should be taken for 5 days for the treatment of simplex herpes and chickenpox, and for 7 days for shingles. If symptoms do not improve after this time, alternative treatments should be considered. Treatment is most effective when started early; for shingles, treatment should be initiated within 5 days of skin symptoms appearing, and for chickenpox, within 3 days of onset. For patients with impaired immune function, intravenous administration should be considered, and adequate hydration is essential when using high doses to prevent dehydration and minimize kidney toxicity. For patients with recurrent genital herpes, the need for continued medication should be carefully reviewed after one year of treatment. While taking this medication, disturbances of consciousness may occur; therefore, caution should be exercised when driving or operating hazardous machinery, especially for patients with reduced kidney function. Interactions may occur when combined with other medications. For example, concomitant use with probenecid may increase the concentration of this medication in the body and slow its excretion. Co-administration with other drugs affecting kidney function may increase the risk of kidney damage. Concomitant use with cimetidine may decrease the excretion of this medication, increasing its serum concentration. Coadministration with theophylline may lead to symptoms of theophylline toxicity. When used with mycophenolate mofetil, concentrations of both drugs may increase. Women who are pregnant or may become pregnant should only use this medication when the benefits outweigh the risks, due to the potential risk of teratogenesis. This medication's ingredients may be excreted in breast milk, necessitating cessation of breastfeeding during treatment. Infants and children should only be given the minimum necessary dose, and special caution should be exercised when administering to neonates or low birth weight infants as safety has not been established. Elderly patients may be at increased risk of prolonged retention of the drug in the body due to reduced kidney function; therefore, dosage and dosing intervals should be adjusted, and adequate hydration should be ensured. In case of overdose, severe symptoms such as agitation, coma, convulsions, and drowsiness may appear, potentially leading to kidney damage. If overdose is suspected, the patient should be closely monitored and plasma drug concentrations measured, and if necessary, measures such as hemodialysis should be implemented to reduce drug levels.

Side effects and when to seek care immediately

Serious side effects

  • Hives
  • severe swelling (edema)
  • chest tightness
  • difficulty breathing
  • cold sweat
  • pallor
  • anaphylaxis
  • anaphylactic-like reactions
  • severe allergic reactions
  • vesicles
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  • hives-like erythema
  • urticaria
  • Stevens-Johnson syndrome
  • toxic epidermal necrolysis
  • jaundice
  • liver dysfunction
  • sudden and very severe headache
  • thunderclap headache
  • seizures
  • confusion
  • visual disturbances
  • paralysis
  • renal failure

Mild side effects

  • Photosensitivity
  • fixed drug eruption
  • rash
  • fever
  • alopecia
  • erythroderma
  • disturbance of consciousness
  • disorientation
  • impaired concentration
  • aggressive behavior
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  • depersonalization
  • agitation
  • ataxia
  • stupor
  • confusion
  • delirium
  • stuttering
  • encephalopathy
  • hallucinations
  • psychosis
  • convulsions
  • drowsiness
  • tremor
  • excitement
  • forgetfulness
  • insomnia
  • anxiety
  • soliloquy
  • paresthesia
  • ataxia
  • impaired gait
  • involuntary movements
  • nystagmus
  • dizziness
  • crystalluria
  • elevated BUN
  • serum creatinine

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be light-sensitive, so it should be stored in a container that blocks light. Additionally, it is recommended to store the medication at room temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the drug's efficacy and safety.

Appearance and packaging

Appearance

White hexagonal tablet

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.