Naja Injection 0.3 mg (Ramosetron Hydrochloride)

Adult administration

Ramosetron Hydrochloride 0.3 mg should be administered intravenously once daily. If effects are insufficient, the same dose may be administered additionally. However, do not exceed 0.6 mg in a single day. Adjust according to symptoms.

This medication is intended for injection and should be handled very carefully to avoid glass fragments when cutting glass containers. Special care is needed when administering to children or the elderly. It should not be administered to patients who have allergic reactions to this medication or its components. Caution is required when administering this medication to patients taking other serotonin-related drugs, and appropriate monitoring per physician's instructions is necessary. Serious allergic reactions such as shock or anaphylaxis may occur when using this medication; if any abnormal symptoms appear, administration should be immediately stopped and appropriate treatment sought. There have been reports of seizure-like episodes, so immediate communication with medical professionals is required if any neurological symptoms occur. Various side effects, such as headache, diarrhea, constipation, liver function abnormalities, itching, and redness, may occur; any unusual symptoms should be consulted with a doctor. Since this medication is primarily metabolized in the liver, caution is required when dealing with patients with impaired liver function or when used in combination with certain drugs. Women who are pregnant or may become pregnant should carefully consider the risks and benefits of using this medication, and breastfeeding should be discontinued if breastfeeding. Safety in children has not been sufficiently validated; therefore, special attention is required when administering to children. Elderly patients may have weakened physical functions, so their condition should be monitored closely during administration, and any adverse reactions should be dealt with immediately. This medication may cause problems if mixed with specific injections, so it is advisable not to mix them during preparation. Ampoules should be wiped with alcohol cotton before cutting to minimize contamination. Finally, toxicity that may affect the fetus has been reported in animal studies, so pregnant women should exercise particular caution.

Serious side effects

shock, anaphylaxis-like symptoms (chest tightness, difficulty breathing, asthma, decreased blood pressure), seizure-like episodes

Mild side effects

headache, feeling of heaviness in the head, diarrhea, constipation, elevated BUN, elevated serum creatinine, liver function abnormalities (elevated AST, elevated ALT, elevated r-GTP, elevated bilirubin), feeling of warmth, hiccups, heat sensation in the head, tingling of the tongue, hypersensitivity (itching, redness, rash), insomnia, rash

This medication should be stored in a sealed container to prevent air from entering and kept in a dark place where direct light does not reach. Additionally, it should be stored at room temperature, between 1℃ and 30℃.

Appearance

This medication is a colorless, clear injection.

Package unit

5 ampoules/box [2mL/ampoule * 5], 10 ampoules/box [2mL/ampoule * 10]