Mucosatin Injection 10% (Acetylcysteine)

Adult administration

1. Mucus dissolution - Intravenous injection: administer 600 to 900 mg of acetylcysteine once 2 to 3 times a day. - Intramuscular injection: administer 300 mg of this medication once or twice a day. 2. Detoxification of acetaminophen poisoning - Initially, administer 150 mg per kg of body weight diluted in 200 mL of 5% dextrose solution over 15 minutes via intravenous drip. - Next, administer 50 mg per kg of body weight diluted in 500 mL of 5% dextrose solution over 4 hours.

Child administration

1. Mucus dissolution - Intravenous injection: administer 300 to 450 mg of this medication 2 to 3 times a day. - Intramuscular injection: administer 150 mg of this medication once or twice a day.

This medication is provided in a glass ampoule form, so care must be taken to avoid glass fragments when opening the container. Extra caution should be exercised when used by children or the elderly. It should not be administered to those who are allergic to this medication or any of its components. Caution should be exercised in patients with bronchial asthma or poor respiratory function as bronchospasm may occur, and if adverse symptoms present, administration should be halted immediately and appropriate treatment sought. It is advisable to avoid use in newborns unless it is not serious. Gastrointestinal side effects such as nausea, vomiting, loss of appetite, and diarrhea may occur when using this medication. Rarely, hypersensitivity reactions such as hives, itching, rash, headache, tinnitus, and bronchospasm may present. Moreover, a rapid heartbeat or high blood pressure may occur very rarely, and very rarely, severe allergic reactions like anaphylaxis may occur. When used as an antidote at high doses via intravenous injection, symptoms similar to hypersensitivity reactions may occur, and severe hypertension may be induced, necessitating caution and immediate cessation of administration at the first sign of adverse symptoms. During usage, bronchial secretions may increase, so thorough observation is required, and if secretions do not drain naturally, appropriate measures such as suctioning or position changes should be implemented. For intramuscular injections, deep injection is recommended. When used for detoxification purposes, it is recommended to administer within 10 hours post-overdose. This medication may engage in chemical reactions when used with specific drugs, so caution is necessary when mixing or co-administering with other medications. There is not enough research regarding its use in pregnant women, so it should only be used when absolutely necessary. Nursing mothers should exercise caution as this medication may be transmitted through breast milk. Elderly patients may have reduced body function, so care should be taken and close monitoring is advised during administration.

Serious side effects

• Hives
• bronchospasm
• anaphylaxis
• respiratory distress
• angioedema

Mild side effects

• Nausea
• vomiting
• loss of appetite
• diarrhea
• itching
• rash
• headache
• tinnitus
• tachycardia
• hypertension

This medication should be stored in a container that protects from light as it may be sensitive to light. Additionally, it is advisable to avoid areas that are too hot or too cold during storage, and keep it at normal room temperature.

Appearance

A brown ampoule containing a colorless and transparent liquid

Package unit

<For domestic use> 50 ampoules (3 mL/ampoule X 50) <For export> 10 ampoules (3 mL/ampoule X 10)