Theolan Biserium Capsule 100 mg (Theophylline)

Adult dose

Adults: Administer orally 200mg of theophylline per dose twice daily at 12-hour intervals. Adjust the dose appropriately according to age and symptoms.

This drug requires caution as high blood concentrations can lead to severe side effects such as seizures or cardiac arrhythmias. It should be used with special care in patients with heart disease. Patients with allergies to this drug or those with ulcers in the stomach or duodenum should not use it. Additionally, patients who have previously experienced severe side effects from similar medications should also avoid administration. Patients with certain conditions such as epilepsy, hyperthyroidism, acute nephritis, congestive heart failure, liver disorders, as well as children and the elderly should use this drug with caution. This medication can cause various side effects including skin rashes, itching, headache, insomnia, dizziness, palpitations, nausea, and vomiting. In case of overdose, serious symptoms such as seizures or coma may occur, which require immediate treatment. It is very important to regularly monitor blood concentrations of this drug to adjust the appropriate dosage. Special attention is required for patients with reduced liver or kidney function, the elderly, and those with heart failure, as the risk of side effects is higher. Drug interactions may occur when taken with other medications, so it is crucial to inform healthcare providers about any medications being taken. Dosage adjustments may be necessary, especially when used with central nervous system stimulants, antibiotics, cardiac drugs, certain antibiotics, and steroids. Pregnant or breastfeeding women should use this drug cautiously under the guidance of a physician, as it may affect the baby. For children, safety has not been established in those under 1 year of age, and particular care should be taken for children with a history of seizures. Older adults may experience increased drug concentrations due to liver function decline, so doses should be reduced and blood concentrations monitored regularly. In case of overdose, symptoms such as vomiting, abdominal pain, cardiac abnormalities, and seizures may appear, necessitating immediate emergency care and potential treatment to assist drug elimination. There have been reports of mutagenicity with long-term use of this drug, so it is essential to consult with healthcare providers when taking it for an extended period.

• Convulsions
• supraventricular tachycardia
• shock
• rash
• itching
• central nervous system excitation
• anxiety
• headache
• insomnia
• dizziness

This drug should be stored in a tightly sealed container to prevent air entry and kept in a cool room away from direct sunlight. This is to maintain the efficacy of the drug and prevent its deterioration.

Appearance

A hard capsule with a green upper part and a colorless transparent lower part containing white to pale yellow sustained release pellets.

Package unit

30 capsules/bottle, 200 capsules/bottle, 500 capsules/bottle