Krabit Injection (Levofloxacin)

Adult administration

Administer by slow intravenous infusion 1 to 2 times a day. Dosage is determined based on the type and severity of infection and the susceptibility of the causative organism, generally transitioning to oral medication after several days of intravenous administration based on the patient's condition. The dosage can be the same as intravenous administration. The administration method includes infusion 1 to 2 times a day for a maximum of 14 days, with a minimum infusion time of 60 minutes. Dosage examples are as follows:

This medication may cause tendon-related conditions such as tendonitis and tendon rupture; thus, if any pain or inflammation in tendons occurs, its use should be stopped immediately. Peripheral neuropathy and central nervous system adverse symptoms may also occur; if such symptoms arise, prompt treatment is needed. Patients with myasthenia gravis should not use this medication, as it can worsen symptoms. The infusion rate must be adhered to during intravenous administration; if blood pressure drops sharply during the infusion, the infusion should be stopped immediately. Elderly patients or those with reduced kidney function, as well as those using corticosteroids concomitantly, are at higher risk of tendon rupture, requiring caution. This medication can increase the risk of seizures in patients with a history of epilepsy or seizures and should be used with caution. It is considered safe not to use this medication in pregnant or breastfeeding women and adolescents under 18. During administration, skin rash, breathing difficulties, or severe allergic reactions may occur; if any unusual symptoms arise, it should be stopped immediately and consultation with a medical professional sought. Dizziness, drowsiness, or visual disturbances may occur during administration, so caution is needed when driving or operating machinery. Diabetic patients requiring blood sugar control should monitor their blood sugar levels closely during the intake of this medication. This medication may interact with other drugs; therefore, patients should notify their healthcare professional, especially if they are taking anticoagulants, certain anti-inflammatory drugs, or diabetes medications. In cases of overdose, central nervous system symptoms and cardiac abnormalities may occur, so the prescribed dosage must be strictly adhered to, and immediate medical help should be sought in case of side effects. This medication may cause sensitivity reactions to sunlight or artificial ultraviolet light; therefore, patients should avoid strong sunlight exposure during administration and stop immediately if skin abnormalities occur. It should be stored in a sealed container to prevent exposure to air and light and kept at room temperature, avoiding direct sunlight.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe skin adverse reactions (toxic epidermal necrolysis, Stevens-Johnson syndrome, DRESS), respiratory issues (bronchospasm, acute respiratory distress, dyspnea), liver abnormalities (jaundice, hepatitis, acute renal failure), severe neurological symptoms (seizures, loss of consciousness, confusion, convulsions, tremors, increased intracranial pressure, epilepsy), severe

Mild side effects

Itching, rash, nausea, diarrhea, loss of appetite, vomiting, abdominal pain, indigestion, abdominal bloating, constipation, headache, dizziness, drowsiness, insomnia, neuroticism, sensory abnormalities, tremors, anxiety, agitation, confusion, perception impairment, visual and auditory disturbances, taste and smell disorders, hallucinations, mania, tachycardia, hypotension, arthralgia, myalgia, bloody stools, syndrome of inappropriate antidiuretic hormone secretion, hypoglycemia, elevated serum creatinine, liver enzyme levels (AST/AL)

This medication should be stored in a sealed container, preventing exposure to air and light. It should be kept at room temperature, avoiding direct sunlight.

Appearance

A clear yellowish-green solution contained in a vial for injection.

Package unit

50mL/vial x 1 vial, 100mL/vial x 1 vial, 150mL/vial x 1 vial