Vancomycin Injection 1g (Vancomycin hydrochloride)

Adult dosage

(Capsule) Administer 500mg (potency) divided into doses for 7-10 days. In the case of severe infections, a total daily dose of 2g (potency) can be divided into 3-4 doses, not exceeding 2g. (Injection) Administer 500mg (potency) every 6 hours or 1g (potency) every 12 hours via intravenous drip. (Oral administration, treatment of enterocolitis and pseudomembranous colitis) 500-200

Children's dosage

(Capsule) Administer 40mg/kg (potency) divided into 3-4 doses daily for 7-10 days, with the total daily dose not exceeding 2g. Adjust according to age and symptoms. (Injection

This medication should not be used in patients who have had an allergic reaction to this drug or its components. Caution should be exercised in patients who have had hypersensitivity reactions to peptide antibiotics or aminoglycosides, those with hearing damage or hearing impairment, those with poor kidney function, the elderly, and those with damage to the vestibular system and cochlea. During the use of this drug, symptoms such as hypotension, dizziness, tinnitus, and sweating may appear, so treatment should be stopped immediately and appropriate care sought if any abnormal symptoms occur. This drug may cause side effects such as decreased white blood cell count, decreased platelet count, hearing loss, and decreased kidney function, hence regular blood tests and monitoring of kidney and hearing functions are necessary. Long-term use may lead to the development of resistant bacteria, so it's important to check the susceptibility of the infecting bacteria and use the drug for the minimum necessary duration. Particularly in patients with impaired renal function or the elderly, the elimination of this drug may be delayed, leading to accumulation in the body, hence dose adjustment and monitoring of renal function are essential. The risk of side effects may increase when this drug is used concomitantly with other neurotoxic or nephrotoxic medications, so all concurrent medications must be reported. Women who are pregnant or breastfeeding should use this drug cautiously under medical supervision, as it may affect the fetus or neonate, and it is advisable to avoid use during breastfeeding or to discontinue breastfeeding during treatment. In cases of overdose, decreased kidney function and hearing damage may occur, so immediate appropriate treatment should be sought at a hospital, as this drug is not easily removed by standard dialysis and special treatment may be required. When used as an injection, this drug must be administered intravenously, and if injected too quickly, it may cause hypotension or cardiac issues; thus, it should be injected slowly. This drug may cause serious skin reactions or severe side effects such as pseudomembranous colitis; if symptoms such as skin rash, severe diarrhea, abdominal pain, or fever occur, immediate consultation with medical personnel is required. Regular blood tests, liver function tests, kidney function tests, and hearing tests are essential while using this drug to monitor the occurrence of side effects.

Serious side effects

Hives, severe swelling, chest tightness, breathing difficulties, cold sweat, pallor, hypotension, severe shock, severe allergic reactions, serious skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis, DRESS, LABD, TEN), rash, blisters, skin peeling, pain in mouth/eye mucosa, respiratory distress, wheezing, jaundice, liver abnormalities (including jaundice), severe neurological symptoms (acute generalized exanthematous pustulosis, eighth cranial nerve dysfunction)

Mild side effects

• Dysgeusia
• dizziness
• constipation
• tinnitus
• sweating
• nausea
• loss of appetite
• chills
• cold sensation
• fever

This drug should be stored in a sealed container to prevent air or moisture exposure. It is best kept at room temperature between 1 and 30 degrees Celsius to maintain its effectiveness.

Appearance

A white to light yellowish-brown freeze-dried powder in a colorless transparent vial for injection

Package unit

10 vials