Medication info

Tobrex 0.3% Eye Drops (Tobramycin)

Prescription medicationEye drops점안
Ingredient · strength
Tobramycin›3mg / 1mL
Manufacturer / importer
한국노바티스(주)
Appearance
A colorless to slightly yellowish transparent liquid contained in an opaque white plastic bottle as an eye drop solution.
Packaging
5mL/bottle
Approval status
Active

MFDS item code 199704517 · Notified 1997.06.11 · Insurance code 653603021

Summary

Main use
Treatment of eye infections such as blepharitis and conjunctivitis
Who applies the drops
Adults
Adult eye dose
For mild to moderate infections, instill 1 to 2 drops in the infected area every 4 hours. For severe infections, instill 2 drops every hour until symptoms improve, then gradually reduce the dosage. Adjust according to age and symptoms.

Ingredients

Importer
한국노바티스(주)

Efficacy & effects

Treatment of eye infections such as blepharitis and conjunctivitis

  • Blepharitis
  • dacryocystitis
  • stye
  • conjunctivitis
  • keratitis
  • corneal ulcers
View approved original text

This drug is effective against various types of bacteria, particularly affecting harmful bacteria such as Staphylococcus aureus, Streptococcus, Pseudomonas aeruginosa, and Escherichia coli. Based on this, it is used in the treatment of inflammatory diseases around the eyes, including blepharitis, dacryocystitis, stye, conjunctivitis, keratitis, and corneal ulcers. It plays an important role in effectively improving these infectious diseases, alleviating patient symptoms and aiding recovery.

How to apply drops

Adult eye dose

For mild to moderate infections, instill 1 to 2 drops in the infected area every 4 hours. For severe infections, instill 2 drops every hour until symptoms improve, then gradually reduce the dosage. Adjust according to age and symptoms.

Precautions

This medication is an aminoglycoside antibiotic and should not be used in patients with a history of hypersensitivity to specific antibiotics or this drug. During use, discomfort such as itching, redness, and pain in the eyes may occur, and rarely symptoms such as headaches or skin rashes may also develop. Long-term use of this medication may lead to resistant bacteria, so it is advisable to use it only for the necessary minimum duration. Prior to administration, it is important to confirm whether any allergic reactions exist, and if hypersensitivity occurs, discontinue use immediately. If wearing contact lenses, they should be removed prior to administration as this drug may discolor or irritate the lenses, and they can be reinserted after some time. After instillation, temporary blurred vision may occur, so driving or operating machinery should be avoided until vision returns to normal. This drug may affect neuromuscular function, so caution is needed for patients with myasthenia gravis or Parkinson's disease. Patients taking anticoagulants may experience an increased risk of bleeding when using this drug, so periodic checks of blood coagulation status are necessary. During pregnancy, it should be used only if necessary, considering the potential effects on the fetus, and for nursing mothers, careful consideration of its effects on the baby is essential. In case of overdose, inflammation, swelling, or itching in the eyes may appear; if these symptoms occur, immediate consultation with healthcare professionals is required. This medication is intended for ophthalmic use only, should be completed within 4 weeks of opening, and when not in use, the bottle should be tightly closed to maintain cleanliness. During administration, care should be taken to avoid contamination by ensuring that the tip of the container does not touch the eye or surrounding area.

Side effects and when to seek care immediately

Serious side effects

  • Rash
  • anaphylactic reaction
  • Stevens-Johnson syndrome
  • erythema multiforme
  • dermatitis

Mild side effects

  • Headache
  • ocular discomfort
  • ocular redness
  • keratitis
  • corneal abrasion
  • vision impairment
  • blurred vision
  • eyelid edema
  • eyelid erythema
  • conjunctival edema
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  • dry eyes
  • increased tear secretion
  • ocular pain
  • ocular itching
  • ocular discharge
  • dermatitis
  • loss of eyebrows
  • hypopigmented skin
  • itching
  • dry skin
  • ocular allergy
  • ocular irritation
  • eyelid itching
  • erythema
  • allergic conjunctivitis
  • temporary burning in the eyes
  • punctate keratitis
  • increased tear production

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to avoid exposure to air and moisture and kept in a cool place at or below 25 degrees Celsius. Storing it this way can help maintain the drug's effectiveness for a longer period.

Appearance and packaging

Appearance

A colorless to slightly yellowish transparent liquid contained in an opaque white plastic bottle as an eye drop solution.

Package unit

5mL/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.