Anflame Tablet (Ofloxacin)

Adult dose

Adults: Usually, take ofloxacin 300～600 mg daily in 2～3 divided doses. For leprosy, take 400～600 mg of this medicine daily in 2～3 divided doses. In principle, use in combination with other antileprosy drugs. Adjust the dose as appropriate according to age and symptoms.

This drug is a fluoroquinolone antibiotic used to treat various infections. However, this drug may cause tendon-related problems such as tendonitis or tendon rupture; if such symptoms occur, usage should be immediately discontinued. Additionally, it may affect peripheral neuropathy or the central nervous system, so caution is needed if sensory abnormalities or neurological symptoms appear. It should not be used in patients with myasthenia gravis as it may worsen symptoms. This drug should not be administered to specific patient groups, such as those with a history of hypersensitivity to quinolone antibiotics, growing children or adolescents, pregnant or breastfeeding women, and patients with certain genetic disorders. Particular caution is necessary when using this drug in patients with impaired renal or liver function, elderly patients, patients with a history of mental illness, or those at risk of aortic aneurysm. This drug can rarely cause serious allergic reactions, liver dysfunction, kidney problems, gastrointestinal disorders, blood abnormalities, neurological symptoms, skin conditions, muscle and joint pain, respiratory problems, and cardiovascular issues. If any abnormal symptoms appear, consult a healthcare provider immediately. Furthermore, this drug may interact with other medications, so if you are taking anticoagulants, diabetes medications, certain antacids, lipid drugs, or antihypertensive medications, be sure to inform your doctor or pharmacist. Be cautious to avoid excessive sunlight exposure while taking this medication, and discontinue use if a rash or skin abnormality develops. This drug should not be used during pregnancy or breastfeeding and is also not recommended for children and adolescents. Elderly patients may need dose adjustments and careful monitoring due to potential impairment of renal function, which can prolong the drug's presence in the body. In case of overdose, symptoms such as drowsiness, dizziness, and numbness may occur, and in such cases, immediate medical attention should be sought. This drug should be administered slowly via intravenous injection, and it is safe not to mix it with other medications during administration. Finally, this drug should be stored in a place out of reach of children, and transferring it to another container can compromise quality.

Tendinitis, tendon rupture, peripheral neuropathy, central nervous system effects, worsening of myasthenia gravis, anaphylactic shock, anaphylactic reactions, rash, itching, erythema, edema, fever, flushing, vesicles, erythema, photosensitivity reactions, hematuria, acute renal failure, kidney stones, interstitial nephritis, elevated BUN, elevated serum creatinine, jaundice, liver failure, elevated AST/ALT, elevated ALP, elevated γ-GTP, elevated total bilirubin, cholestatic jaundice, fulminant hepatitis, membranous colitis, abdominal pain, frequent diarrhea, nausea, vomiting, gastrointestinal discomfort, diarrhea, cirrhosis, appetite loss, abdominal discomfort, indigestion, chest pain, thirst, taste disturbance, stomatitis, glossitis, abdominal bloating, constipation, dysphagia, gastrointestinal bleeding, oral mucositis, intestinal perforation, anemia, leukopenia, decreased hemoglobin, decreased hematocrit, thrombocytopenia, eosinophilia, agranulocytosis, thrombotic thrombocytopenic purpura, petechiae, prolonged prothrombin time, reversible bone marrow suppression, lymphocytopenia, neutropenia, elevated ESR, insomnia, dizziness, headache, seizures, tremors, numbness, peripheral neuropathy, visual disturbances, auditory disturbances, hallucinations, drowsiness, neuroexcitability, sleep disturbances, confusion, anxiety, depression, agitation, euphoria, disorientation, attention deficit, memory impairment, delirium, suicidal ideation, suicide, perceptual disturbances, olfactory and equilibrium sensory disturbances, ataxia, aphasia, heaviness of head, skin and mucous membrane syndrome, toxic epidermal necrolysis, arthralgia, myalgia, muscle weakness, myositis, fatigue, elevated CPK, elevated myoglobin, rhabdomyolysis, pharyngitis, dyspnea, bronchospasm, allergic pneumonia, epistaxis, stridor, fever, cough, abnormal chest X-ray, eosinophilia, interstitial lung disease, cerebral thrombosis, pulmonary edema, tachycardia, hypertension, hypotension, palpitations, vasodilation, circulatory collapse, QT prolongation, ventricular tachycardia, dysuria, frequent urination, urinary retention, anuria, polyuria, hematuria, urinary storage, pyuria, diabetes, proteinuria, alkaline urine, vaginitis, vaginal candidiasis, increased vaginal discharge, vulvar itching, menstrual irregularities, uterine cramps, women's genital rash, pain, irritation, burning sensation, hypoglycemic symptoms, limb pain, malaise, fever

This drug should be stored in a tightly closed container to prevent air ingress, ideally at room temperature between 1 degree and 30 degrees Celsius. Proper storage will help maintain the drug's effectiveness and prevent deterioration.

Appearance

Round film-coated tablets, white to off-white

Package unit

30 tablets/bottle, 500 tablets/bottle