Tinidazole Tablets

Adult dosage

1. Trichomoniasis and giardiasis Adults: Administer 2g of tinidazole orally as a single dose, or administer 150mg per dose 3 times daily for 5 days or 150mg per dose twice daily for 7 days. 2. Anaerobic bacterial infections As this medicine, the usual adult dose is 2g as a single dose on the first day, followed by 1g once daily from the next day, or 500mg per dose twice daily by mouth. Prevention of postoperative infections: Administer 2g orally as a single dose 12 hours before surgery. Acute ulcerative gingivitis: Administer 2g orally as a single dose. 3. Amebiasis Adults: Administer 2g of this medicine orally once daily for 2～3 days. 4. Nonspecific vaginitis As this medicine, the usual adult dose is 2g once daily for 1～2 days. * Adjust the dose as appropriate according to age and symptoms. * Take with food.

Children's dosage

Trichomoniasis and giardiasis: Administer 50～75mg per kg of body weight as a single dose. Amebiasis: Administer 50～60mg per kg of body weight once daily for 3 days.

This medication should not be used in certain patients. First, patients who are allergic to this medication or similar drugs, those with blood disorders or a history of such conditions, patients with neurological issues, and women who are pregnant or nursing should not take this medication. Additionally, patients with severely impaired liver function should be cautious as this medication can be slowly broken down in the body and accumulate in the blood. Patients with a fungal infection known as candidiasis may experience worsening symptoms during treatment with this medication and may require concurrent antifungal therapy. Various side effects may occur during the use of this medication. Gastrointestinal side effects may include occasional nausea, vomiting, loss of appetite, diarrhea, a metallic taste in the mouth, and a white coating on the tongue. Allergic reactions such as skin rash, hives, itching, and angioedema in the face or neck area may occur. Blood-related problems may cause joint swelling or a temporary decrease in white blood cell count. In the genital area, candidal vaginitis may develop. Other side effects may include headache, heavy sensation in the head, fatigue, dry mouth, and darkening of urine color. Avoid alcohol consumption while taking this medication. Taking alcohol together may lead to uncomfortable symptoms such as nausea, vomiting, headache, and dizziness, and it is advisable not to drink alcohol during the treatment period and for 3 days after stopping the medication. Moreover, if dizziness, lack of coordination, or symptoms of motor dysfunction appear, stop taking the medication immediately and consult a doctor. This medication may interact with other drugs, so caution is necessary. In particular, it can significantly enhance the effects of blood thinners like warfarin, requiring dosage adjustments during and up to 8 days after discontinuation of tinidazole. It may also increase the plasma concentration of lithium, delay the breakdown of phenytoin, an antiepileptic drug, and increase concentrations of immunosuppressants such as cyclosporine or tacrolimus, potentially escalating the side effects of certain chemotherapeutic agents. This medication may also reduce the efficacy of some antibiotics. Pregnant women should be especially cautious with this medication. Animal studies indicate that high doses may impact the fetus, and because it crosses the placenta, it is safest not to take this medication during the first three months of pregnancy. In the later stages of pregnancy, it should only be used if a doctor determines that the benefits outweigh the risks. Additionally, since this medication is passed through breast milk, it is essential to discontinue breastfeeding during treatment. The safety and efficacy of this medication have not been sufficiently established in children, especially those under 3 years of age. Lastly, in cases of overdose, there is no specific antidote, so it is important to receive emergency treatment such as gastric lavage and symptomatic care.

• nausea
• vomiting
• anorexia
• diarrhea
• metallic taste
• coated tongue
• erythema
• urticaria
• pruritus
• angioedema

This medication should be stored in a tightly sealed container that blocks light and is suitable for storage at room temperature. Therefore, it is advisable to avoid direct sunlight and to store it in a place that is not too hot or too cold.

Appearance

It is a pale yellow-brown, round tablet.

Package unit

10, 50, 100, 500, 1000 tablets