Huons Lidocaine Hydrochloride Hydrate Injection 1%

Adult administration

For liquid preparation 2% viscosity: The maximum single dose should not exceed 4.5 mg per kg of body weight, and the total dose should not exceed 300 mg (15 mL of this medication). For symptomatic treatment of oral and pharyngeal mucosal irritation and inflammation, administer 300 mg. For oral use, swish and then spit, and for throat use, swish and then swallow. Do not reuse within 3 hours; do not use more than 8 times in 24 hours. For gel 2% urethral anesthesia: males 20 mL.

This medication should be cut very carefully when opening the ampoule, as glass particles can get mixed in. Extra caution is required when used on children or the elderly. This medication should not be used in patients with severe bleeding or shock, patients with inflammation at the injection site, patients with septicemia, and individuals allergic to this medication or similar local anesthetics. Caution should be exercised when used in patients with central nervous system diseases, pregnant women, elderly patients, severe hypertension, and patients with marked spinal deformities. During use, symptoms such as decreased blood pressure, facial pallor, heart rhythm irregularities, and respiratory depression may occur; thus, careful monitoring is essential. Severe side effects such as high fever, muscle rigidity, respiratory distress, sweating, and acidosis may occur. If these symptoms appear, administration must be stopped immediately and appropriate treatment initiated. It may affect the central nervous system causing symptoms like tremors, seizures, drowsiness, anxiety, dizziness, and nausea; appropriate action should be taken if symptoms arise. Allergic reactions such as skin rashes or swelling may occur, so notify medical personnel of any abnormal symptoms. When using this medication, the lowest possible concentration and minimum dosage should be used to minimize the risk of side effects, ensuring that the injection site is checked to prevent intravascular injection and administering slowly. When used together with vasoconstrictors, caution is necessary in patients with certain diseases or allergy history, considering potential drug interactions; discuss with healthcare providers about other medications being taken. Women who are pregnant or may become pregnant should only use this medication when the benefit outweighs the risk, and elderly patients should be cautious with dosage adjustments due to potential increased medication concentration. This medication is not intended for ophthalmic use, and prolonged use at high concentrations may increase the risk of mutations and tumor development; thus, avoid prolonged high-concentration use.

Serious side effects

Urticaria, swelling, facial pallor, shock, chest tightness, difficulty breathing, facial pallor, low blood pressure, cardiac arrest, anaphylactic reaction, malignant hyperthermia (sudden increase in body temperature with fever, muscle rigidity, cyanosis, myoglobinuria), respiratory depression, central nervous system toxicity symptoms (tremors, seizures, convulsions), altered consciousness, paralysis, vision disturbances, severe neurological symptoms due to toxicity, jaundice (related to liver abnormalities), renal failure, decreased urine output, severe.

Mild side effects

Drowsiness, anxiety, agitation, indifference, dizziness, nausea, vomiting, confusion, feelings of euphoria, numbness, tremors, seizures, low blood pressure, abnormal pulse, blood pressure variability, sweating, hyperventilation, acidosis, hyperkalemia, myoglobinuria (red urine), correction of acid-base balance, body cooling, administering dantrolene sodium intravenously, diazepam or ultra-short-acting barbiturate administration, continuous blood pressure monitoring and ECG monitoring, confirming the position of the injection needle, injection.

This medication should be stored in a sealed container to prevent exposure to air or moisture. Additionally, it is recommended to keep it in a cool place, avoiding direct sunlight.

Appearance

A colorless injection in an ampoule or vial filled with a clear and transparent liquid.

Package unit

- For domestic use: 20mL x 10 vials - For export: 5mL x 10 ampoules, 5mL x 25 ampoules, 5mL x 10 vials, 5mL x 25 vials, 20mL x 25 vials