Alpha Min Ju

Adult administration

A maximum of 1 - 1.5 g of total amino acids is administered intravenously per day per kg of body weight. The infusion rate should comfortably allow for a concentration of approximately 10 g of total amino acids over 60 minutes, with the principle being 30 - 40 drops per minute.

Child administration

In children, dosage and infusion rates should be adjusted accordingly.

This medicine must be used under a physician's direction. Do not administer to patients with hepatic coma or those at risk of hepatic coma, patients with severe renal impairment, or patients with hypernitrogenemia. Should not be used in patients with metabolic disorders that make it difficult to utilize nitrogen, patients with decompensated heart failure, patients with pulmonary edema, or patients with oliguria or anuria. If the product contains sodium or chloride ions, it should not be administered to patients with hypernatremia, hyperchloremia or alkalosis, and caution is required for patients with a history of myocardial infarction or current myocardial infarction. Exercise caution in patients with severe acidosis, congestive heart failure, edema due to sodium retention, and hyperkalemia or potassium retention. Patients with liver or kidney function problems should be especially cautious. This medication contains sodium bisulfite which can cause allergic reactions, especially anaphylaxis or asthma attacks, so asthmatic patients should be especially cautious. Rarely, hypersensitivity reactions such as rash may occur, and gastrointestinal symptoms such as nausea or vomiting may also occur. Cardiovascular symptoms such as palpitations, rapid pulse, and elevated blood pressure have also been reported. Rapid mass administration may lead to metabolic acidosis, so caution is required. Various adverse reactions such as chills, fever, headache, dyspnea, shock, bronchospasm, and urinary tract spasm may occur. Metabolic complications such as metabolic acidosis, hypophosphatemia, alkalosis, hyperglycemia, diabetes, and dehydration may occur. Patients with impaired liver or kidney function may have elevated specific blood values, and those with hepatic failure may exhibit serious symptoms such as coma or loss of consciousness. Mass administration may lead to electrolyte imbalances, so electrolyte levels should be monitored regularly. This medicine may reduce the protein-sparing effect when used with tetracycline class antibiotics. Safety in pregnant women has not been established, and it should only be used if the therapeutic benefits outweigh the risks. Children, especially those with immature kidneys, require careful adjustment of drug concentration and frequent monitoring of blood ammonia levels. Elderly patients may have decreased bodily function, so the administration rate should be slow, and the dose should be adjusted. This medication contains electrolytes, so caution should be exercised regarding electrolyte balance when administered in large amounts or when used with other electrolyte solutions. If administered too quickly, chills or vomiting may occur, so it should be infused slowly. Maintain the solution at body temperature, and ensure strict aseptic conditions are maintained during preparation and handling to reduce the risk of infection. Before use, ensure that the solution is completely transparent and do not use if there is any discoloration or leakage. During storage, do not open the packaging, and do not use if the rubber stopper protective film has peeled off. The solution should be used within 24 hours if refrigerated, and if crystals form, it should be properly warmed to dissolve before use.

Serious side effects

Hives, dyspnea, asthma attacks, shock, bronchospasm, anaphylactic shock, severe edema with elevated blood pressure

Mild side effects

• Rash
• nausea
• vomiting
• chest discomfort
• palpitations
• rapid pulse (tachycardia)
• elevated blood pressure
• acidosis
• chills
• fever

Store this medicine in a sealed container to prevent air or moisture from entering, and maintain a storage temperature at room temperature, meaning a general room temperature that is not too hot or too cold. Storing it this way can help maintain the effectiveness of the drug for a longer duration.

Appearance

Colorless, transparent injection solution in a glass bottle with a colorless and transparent rubber stopper for injectable use

Package unit

500 mL / bottle