Nelson Cephradine Capsule 500 mg (Cephradine Hydrate)

Adult dose

○ Adults 1) Skin and soft tissue infections, respiratory tract infections: Depending on the severity, administer 250mg～500mg (potency) of cefradine orally 4 times daily or 500mg～1g (potency) 2 times daily. 2) Urinary tract infections: For uncomplicated urinary tract infections, administer 500mg (potency) 2 times daily. For severe urinary tract infections, administer 500mg (potency) 4 times daily or 1g (potency) 2 times daily. Severe infections may also require an extended treatment period and intensive treatment. ○ Patients with renal impairment 1) For patients not undergoing hemodialysis, administer as follows. Creatinine clearance (mL/min) Dose per administration (mg) Dosing interval (hours) >20 500 6～12 15～20 250 12～24 10～14 250 24～40 5～9 250 40～50 <5 250 50～70 2) For patients undergoing chronic, intermittent hemodialysis, administer an initial dose (first dose) of 250mg (potency) at the start of hemodialysis, then administer 250mg (potency) 6～12 hours and 36～48 hours later, respectively. Administer 250mg at the next hemodialysis session (only if at least 30 hours have elapsed since the most recent dose). Adjust the dose appropriately according to age and symptoms.

Child dose

Children: Administer 25～50mg (potency) per Kg of body weight per day orally in 2～4 divided doses. However, do not exceed 4g (potency) per day or the adult dose. For otitis media, administer 75～100mg (potency) per Kg of body weight per day in 2～4 divided doses. However, do not exceed 4g (potency) per day or the adult dose. It is preferable not to administer to infants 9 months of age or younger.

This drug should not be used in patients who previously experienced severe allergic reactions or shock from this medication. Patients with allergies to this drug or similar antibiotics must use it with caution, and those who have had allergic reactions to penicillin group drugs should also be administered with care. Moreover, patients with a family history of frequent allergic symptoms such as asthma, skin rash, and hives should be careful. Patients with severely impaired kidney function, those who have difficulty swallowing medications, the elderly, and those with poor overall health should be closely monitored for signs of vitamin K deficiency. This medication contains the dye Yellow No. 5, so caution is advised for patients who are allergic to this ingredient. If symptoms such as oral discomfort, shortness of breath, dizziness, or sweating occur during the medication, the drug should be discontinued immediately and healthcare personnel should be notified. If allergic reactions such as skin rash, itching, red spots, swelling, or joint pain occur, the drug should be stopped and appropriate treatment obtained. It is also important to consult healthcare personnel immediately if gastrointestinal symptoms occur, such as abdominal pain, diarrhea, nausea, vomiting, or heartburn. If breathing difficulties, coughing, or fever appear, medication should be stopped and treated. Regular blood tests may be necessary as leukopenia or anemia may appear in blood tests. Rarely, serious skin conditions or liver function abnormalities and kidney dysfunction may occur, so the patient's condition should be carefully monitored. Oral inflammation or candida infections may also arise, so notify healthcare personnel if symptoms appear. Vitamin K or vitamin B deficiency symptoms may also occur occasionally, necessitating caution. If there are symptoms such as headache, fatigue, or abdominal discomfort, it is also advisable to consult healthcare personnel. This medication should only be used for the necessary duration to prevent the occurrence of resistant bacteria, and allergy responses should be verified before administration, with preparations for emergencies. Caution should be observed when taken with other diuretics or certain antibiotics, as it may affect kidney function. Women who are pregnant or may become pregnant should carefully consider the risks and benefits of using this medication, and those who are breastfeeding should also be cautious. It is not safe to administer to infants, especially those under 9 months of age. The elderly may experience increased side effects due to decreased physical function, so dosages and intervals should be adjusted, with close monitoring of their condition. Some urine tests may yield false positive results while taking this medication, so this should be noted to healthcare personnel during testing.

Shock

This medication should be stored in a tightly sealed container to prevent air and moisture from entering. It is advisable to maintain the storage temperature between 1 and 30 degrees Celsius at room temperature. This will help maintain the drug's effectiveness for a longer period.

Appearance

Hard capsules with a reddish-brown upper part and yellow lower part containing a white to light yellow powder.

Package unit

30 capsules/bottle, 300 capsules/bottle