Cozoltec Tablets (Cetirizine Hydrochloride)

Adult dosage

For adults and children aged 6 and above, the dosage is 10 mg of cetirizine hydrochloride taken orally once daily before bed. For patients sensitive to adverse reactions, it may be divided into 5 mg doses taken in the morning and evening. Adjust the dosage according to age and symptoms. For patients with renal impairment, the dosing interval should be adjusted based on renal function. The dosage and frequency should be adjusted according to creatinine clearance, where normal (≥80 mL/min) is 10 mg once daily.

Children's dosage

For children aged 6 and above, the dosage is the same as for adults: 10 mg of cetirizine hydrochloride taken orally once daily before bed. For pediatric patients with renal impairment, the dosage should be adjusted individually according to the patient’s renal clearance and weight.

This medicine should not be taken by individuals allergic to hydroxyzine or piperazine derivatives or those who have experienced hypersensitivity reactions. Patients with severely impaired kidney function, especially those with a creatinine clearance of less than 10 mL/min, should not use this medicine. Children under 6 years old should not take this medication. As this medicine contains lactose, individuals with lactose intolerance or congenital lactose metabolism disorders should not take it. During treatment, this medicine should not be taken with certain drugs, such as theophylline or ritonavir, as interactions may affect drug efficacy. Excessive consumption of alcohol while taking this medicine should be avoided. If you have issues with kidney or liver function or are elderly, consult a healthcare professional before taking this medication, as the blood concentration of this drug may increase. Patients with epilepsy or at risk of seizures should also consult a specialist before taking it. Care should be taken when administering this drug to patients with conditions that may impede urination. Pregnant women should consult a doctor before taking this medicine, and breastfeeding women should be cautious as it may be excreted in breast milk and affect the baby. If severe side effects or allergic symptoms occur while taking this medicine, stop immediately and consult a healthcare professional. In case of overdose, central nervous system symptoms such as confusion, drowsiness, and dizziness may occur, and there is no specific antidote; treatment based on symptoms should be provided. It is advisable to discontinue this medicine before allergy testing, and caution is needed when driving or operating machinery. Taking this medicine with food may slow absorption, but it does not affect the total amount absorbed. Keep out of reach of children and store in the original container to maintain the quality of the drug.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), profound lethargy, sudden and severe headache, lightning headache, seizure, altered consciousness, visual disturbances, paralysis, significantly decreased urine output.

Mild side effects

• Confusion
• diarrhea
• dizziness
• fatigue
• headache
• lethargy
• dilated pupils
• itching
• anxiety
• sedation

Drug interactions

Do not take this medicine with theophylline or ritonavir.

Food interactions

Do not take this medicine with excessive amounts of alcohol.

This medicine may be sensitive to air and moisture, so it should be stored in a tightly sealed container. Additionally, the medication should be kept at room temperature, avoiding extreme heat or cold.

Appearance

White rectangular film-coated tablet

Package unit

For domestic use: 10 tablets/PTP x 1, for export: 10 tablets/PTP x 1, 100 tablets (10 tablets/PTP x 10)