Castor Tablet (Roxithromycin)

Adult dose

(Tablets) Adults: Administer roxithromycin 150㎎ (potency) orally twice daily, in the morning and evening before meals. For pneumonia, administer 300mg (potency) once daily before breakfast. The dose may be adjusted according to age and symptoms.

Child dose

(Pediatric tablets) (Granules) (Oral suspension) Children: The average dose used in clinical trials was 6mg (potency) per kg of body weight per day. This medicine is administered orally in 2 divided doses of 5～8mg (potency) per kg of body weight per day. The doses according to body weight are as follows. Children weighing 6～11Kg: Take 25mg (potency) per dose twice daily before meals (pediatric tablets and granules only); take 2.5mL per dose twice daily before meals (oral suspension only). Children weighing 12～23Kg: Take 50mg (potency) per dose twice daily before meals (pediatric tablets and granules only); take 5mL per dose twice daily before meals (oral suspension only). Children weighing 24～40Kg: Take 100mg (potency) per dose twice daily before meals (pediatric tablets and granules only); take 10mL per dose twice daily before meals (oral suspension only).

This medication can occasionally cause serious skin reactions such as Stevens-Johnson syndrome or toxic epidermal necrolysis, which are severe blistering skin reactions. If symptoms such as blistering of the skin or mucosal damage appear, discontinue use immediately. This medication should not be used by those with an allergy to this medication or macrolide antibiotics, and those taking certain heart-related medications (terfenadine, astemizole, cisapride, pimodidine) or ergot alkaloids. Caution is advised for patients with impaired liver function or elderly patients, as it may affect heart rhythm. Patients with heart diseases or those taking related medications should be careful. Various side effects such as allergic reactions, liver dysfunction, gastrointestinal disorders, and rarely, severe colitis or pneumonia, neurological disorders, hearing and vision issues may occur, and if abnormal symptoms arise, consult a healthcare professional immediately. To prevent the development of drug-resistant bacteria, it should only be used for the necessary duration, and patients with compromised liver function should undergo regular check-ups and dosage adjustments. This medication may interact with various drugs; therefore, inform your physician or pharmacist if you are taking other medications, especially when using with heart-related drugs, anticoagulants, immunosuppressants, sedatives, etc. Women who are pregnant or may become pregnant should carefully consider the risks and benefits before using this medication. In breastfeeding cases, it is advisable to either avoid use or stop breastfeeding. There is no need for dosage adjustment in the elderly, but be cautious of symptoms such as dizziness or blurred vision while driving or operating machinery. Lastly, keep this medication out of reach of children and avoid transferring it to other containers.

Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, shock, anaphylactic shock, fever, rash, allergic skin reaction, angioedema, eosinophilia, agranulocytosis, leukopenia, thrombocytopenia, cholestatic acute hepatitis, hepatocellular acute hepatitis, jaundice, elevated AST, elevated ALT, elevated ALP, elevated serum bilirubin, loss of appetite, nausea, vomiting, discomfort in the upper abdomen, dyspepsia, gastric pain, abdominal pain, abdominal distension, diarrhea, membranous colitis, loose stools, hemorrhagic colitis, blood in stool, pancreatitis, bronchospasm, cough, dyspnea, abnormal chest X-ray, interstitial pneumonia, drowsiness, headache, dizziness, tongue numbness, paralysis, dysgeusia, ageusia, anosmia, loss of smell, erythema multiforme, purpura, superinfection due to the overgrowth of non-susceptible pathogens, transient hearing loss, auditory impairment, visual impairment, blurred vision, conjunctival injection, generalized malaise, weakness, palpitations, QT prolongation, ventricular tachycardia, arthralgia, epistaxis, menstrual irregularities, inflammation of the oral and vaginal mucosa, hallucinations, confusion

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture, and it is recommended to store it at room temperature away from direct sunlight. Storing it this way can maintain the medication's effectiveness for a longer time.

Appearance

White, round, biconvex film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle